G L Vogel1, L C Chow, C M Carey. 1. American Dental Association Foundation, Paffenbarger Research Center, Gaithersburg, MD 20899-8546, USA. jvogel@nist.gov
Abstract
BACKGROUND: Large increases in salivary fluoride were reported 1 h after a calcium pre-rinse/NaF rinse. AIMS: This study examined the persistence of these increases. METHODS: 12 subjects rinsed in the evening with water, with a 228 microg/g (ppm) F rinse or with 150 mmol/l calcium lactate followed by a 228 microg/g F rinse. In a second experiment these same patients rinsed with a 912 microg/g F rinse. Saliva samples were obtained the morning after rinsing, centrifuged and the supernatants analyzed. RESULTS: The Ca pre-rinse/228 microg/g F rinse induced an increase in overnight salivary F over the 912 microg/g F rinse (approximately 2.5 times) and a statistically significant increase over the 228 mug/g F rinse (approximately 5.5 times). CONCLUSIONS: The results suggest that a Ca pretreatment may increase the cariostatic effect of topical F agents. Copyright 2008 S. Karger AG, Basel.
RCT Entities:
BACKGROUND: Large increases in salivary fluoride were reported 1 h after a calcium pre-rinse/NaFrinse. AIMS: This study examined the persistence of these increases. METHODS: 12 subjects rinsed in the evening with water, with a 228 microg/g (ppm) F rinse or with 150 mmol/l calcium lactate followed by a 228 microg/g F rinse. In a second experiment these same patients rinsed with a 912 microg/g F rinse. Saliva samples were obtained the morning after rinsing, centrifuged and the supernatants analyzed. RESULTS: The Ca pre-rinse/228 microg/g F rinse induced an increase in overnight salivary F over the 912 microg/g F rinse (approximately 2.5 times) and a statistically significant increase over the 228 mug/g F rinse (approximately 5.5 times). CONCLUSIONS: The results suggest that a Ca pretreatment may increase the cariostatic effect of topical F agents. Copyright 2008 S. Karger AG, Basel.