Literature DB >> 18780606

Massive hepatic hemangioendothelioma and consumptive hypothyroidism.

Frances Mouat1, Helen M Evans, Wayne S Cutfield, Paul L Hofman, Craig Jefferies.   

Abstract

Hypothyroidism was diagnosed in an infant with massive hepatic hemangioendothelioma. Markedly elevated serum reverse-triiodothyronine levels confirmed consumptive hypothyroidism. Large doses of thyroxine were initially required to normalise TSH. Thyroxine was tapered as the tumor regressed and was discontinued at 16 months old. Thyroid function remains normal without treatment.

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Year:  2008        PMID： 18780606     DOI： 10.1515/jpem.2008.21.7.701

Source DB:  PubMed          Journal:  J Pediatr Endocrinol Metab        ISSN： 0334-018X            Impact factor:   1.634


  5 in total

Review 1.  Transient hypothyroidism in the newborn: to treat or not to treat.

Authors:  Neelakanta Kanike; Ajuah Davis; Prem S Shekhawat
Journal:  Transl Pediatr       Date:  2017-10

2.  Increased type 3 iodothyronine deiodinase activity in a regrown hepatic hemangioma with consumptive hypothyroidism.

Authors:  Kazuhiko Bessho; Yuri Etani; Hiroaki Ichimori; Yoko Miyoshi; Noriyuki Namba; Akihiro Yoneda; Takaharu Ooue; Tsuyoshi Chihara; Eiichi Morii; Tomoyuki Aoki; Masami Murakami; Sotaro Mushiake; Keiichi Ozono
Journal:  Eur J Pediatr       Date:  2009-06-23       Impact factor: 3.183

3.  Consumptive Hypothyroidism: Case Report of Hepatic Hemangioendotheliomas Successfully Treated with Vincristine and Systematic Review of the Syndrome.

Authors:  Marina Weber Pasa; Rafael Selbach Scheffel; André Borsatto Zanella; Ana Luiza Maia; José Miguel Dora
Journal:  Eur Thyroid J       Date:  2017-10-13

Review 4.  Type 3 deiodinase and consumptive hypothyroidism: a common mechanism for a rare disease.

Authors:  Cristina Luongo; Luigi Trivisano; Fausta Alfano; Domenico Salvatore
Journal:  Front Endocrinol (Lausanne)       Date:  2013-09-04       Impact factor: 5.555

5.  Resolution of Consumptive Hypothyroidism Secondary to Infantile Hepatic Hemangiomatosis with a Combination of Propranolol and Levothyroxine

Authors:  Victoria Campbell; Rachel Beckett; Noina Abid; Susannah Hoey
Journal:  J Clin Res Pediatr Endocrinol       Date:  2018-02-28
  5 in total

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