Literature DB >> 18780385

N-Methyl scanning mutagenesis generates protease-resistant G protein ligands with improved affinity and selectivity.

Stephen V Fiacco1, Richard W Roberts.   

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Year:  2008        PMID： 18780385      PMCID： PMC2962921          DOI： 10.1002/cbic.200800208

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  10 in total

1.  In vitro selection of state-specific peptide modulators of G protein signaling using mRNA display.

Authors:  William W Ja; Richard W Roberts
Journal:  Biochemistry       Date:  2004-07-20       Impact factor: 3.162

2.  N-methylation of peptides on selected positions during the elongation of the peptide chain in solution phase.

Authors:  M Luisa Di Gioia; Antonella Leggio; Angelo Liguori
Journal:  J Org Chem       Date:  2005-05-13       Impact factor: 4.354

3.  A peptide core motif for binding to heterotrimeric G protein alpha subunits.

Authors:  William W Ja; Anirban Adhikari; Ryan J Austin; Stephen R Sprang; Richard W Roberts
Journal:  J Biol Chem       Date:  2005-07-28       Impact factor: 5.157

4.  Structural basis for nucleotide exchange on G alpha i subunits and receptor coupling specificity.

Authors:  Christopher A Johnston; David P Siderovski
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-30       Impact factor: 11.205

5.  Convenient synthesis of N-methylamino acids compatible with Fmoc solid-phase peptide synthesis.

Authors:  Eric Biron; Horst Kessler
Journal:  J Org Chem       Date:  2005-06-24       Impact factor: 4.354

6.  Design of cyclic peptides that bind protein surfaces with antibody-like affinity.

Authors:  Steven W Millward; Stephen Fiacco; Ryan J Austin; Richard W Roberts
Journal:  ACS Chem Biol       Date:  2007-09-21       Impact factor: 5.100

7.  Solid-phase synthesis and characterization of N-methyl-rich peptides.

Authors:  M Teixidó; F Albericio; E Giralt
Journal:  J Pept Res       Date:  2005-02

8.  Encodamers: unnatural peptide oligomers encoded in RNA.

Authors:  Adam Frankel; Steven W Millward; Richard W Roberts
Journal:  Chem Biol       Date:  2003-11

9.  Peptoids: a modular approach to drug discovery.

Authors:  R J Simon; R S Kania; R N Zuckermann; V D Huebner; D A Jewell; S Banville; S Ng; L Wang; S Rosenberg; C K Marlowe
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

10.  Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.

Authors:  J T Nguyen; C W Turck; F E Cohen; R N Zuckermann; W A Lim
Journal:  Science       Date:  1998-12-11       Impact factor: 47.728
  10 in total
  7 in total

1.  Peptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution.

Authors:  Halina M Werner; Chino C Cabalteja; W Seth Horne
Journal:  Chembiochem       Date:  2015-08-20       Impact factor: 3.164

2.  Cell-Permeable Peptides Containing Cycloalanine Residues.

Authors:  Hao Wu; Guillaume Mousseau; Sonia Mediouni; Susana T Valente; Thomas Kodadek
Journal:  Angew Chem Int Ed Engl       Date:  2016-08-16       Impact factor: 15.336

3.  Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides.

Authors:  Yu Gao; Thomas Kodadek
Journal:  Chem Biol       Date:  2013-03-21

4.  Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications.

Authors:  Stephen V Fiacco; Lindsay E Kelderhouse; Amanda Hardy; Yonatan Peleg; Biliang Hu; Argentina Ornelas; Peiying Yang; Seth T Gammon; Shannon M Howell; Pin Wang; Terry T Takahashi; Steven W Millward; Richard W Roberts
Journal:  Chembiochem       Date:  2016-07-28       Impact factor: 3.164

Review 5.  Directing evolution of novel ligands by mRNA display.

Authors:  Golnaz Kamalinia; Brian J Grindel; Terry T Takahashi; Steven W Millward; Richard W Roberts
Journal:  Chem Soc Rev       Date:  2021-06-24       Impact factor: 60.615

Review 6.  Strategies towards Targeting Gαi/s Proteins: Scanning of Protein-Protein Interaction Sites To Overcome Inaccessibility.

Authors:  Britta Nubbemeyer; Anna Pepanian; Ajay Abisheck Paul George; Diana Imhof
Journal:  ChemMedChem       Date:  2021-03-22       Impact factor: 3.466

7.  A Machine Learning Bioinformatics Method to Predict Biological Activity from Biosynthetic Gene Clusters.

Authors:  Allison S Walker; Jon Clardy
Journal:  J Chem Inf Model       Date:  2021-05-27       Impact factor: 4.956
  7 in total

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