| Literature DB >> 18780196 |
Anu Koskela1, Tomi Kauppinen, Anna Keski-Rahkonen, Elina Sihvola, Jaakko Kaprio, Aila Rissanen, Aapo Ahonen.
Abstract
The neurotransmitter serotonin (5-HT) controls several physiological functions, and a disturbance of the 5-HT system is implicated in many psychiatric conditions. Seasonal variation has been suggested in the 5-HT system. We investigated within-subject seasonal variation in brain serotonin transporter (SERT) binding with the SERT-ligand [(123)I]ADAM and single photon emission computed tomography (SPECT) in 12 healthy individuals. No systematic variation was found in the midbrain or thalamus areas between scans done in summer and winter. Our results suggest that factors other than season are more important in causing within-subject variation of brain SERT binding between summer and winter.Entities:
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Year: 2008 PMID： 18780196 DOI： 10.1080/07420520802380000
Source DB: PubMed Journal: Chronobiol Int ISSN： 0742-0528 Impact factor: 2.877