BACKGROUND: Patients with established coronary heart disease (CHD) are encouraged to be physically active to prevent disease progression and to prolong life. The amount and intensity of exercise required for risk reduction in patients with CHD is not yet fully resolved. DESIGN: Population-based prospective cohort study with 18 years of follow-up. METHODS: A linkage between a Norwegian population-based study (Nord-Trøndelag health study) and the Cause of Death Registry at Statistics Norway. Exercise amount and intensity were measured at baseline (1984-1986) in 2137 men and 1367 women with CHD. RESULTS: During 18 years of follow-up, 1741 (81.6%) men and 1100 (80.5%) women died. Compared with the reference category (no activity), one weekly exercise session was associated with a lower all-cause mortality, both in men (relative risk 0.80, 95% confidence interval 0.68-0.94) and women (relative risk 0.68, 95% confidence interval 0.55-0.83). This inverse association became stronger with increasing frequency (P< or =0.001 for men and women). Those who reported moderate or high-intensity exercise had a somewhat lower risk of death than those who exercised with low intensity. CONCLUSION: Exercise training reduced all-cause and cardiovascular mortality in men and women with CHD. This study adds significantly to the sparse literature regarding prospective data on physical activity, exercise intensity and mortality in CHD patients.
BACKGROUND:Patients with established coronary heart disease (CHD) are encouraged to be physically active to prevent disease progression and to prolong life. The amount and intensity of exercise required for risk reduction in patients with CHD is not yet fully resolved. DESIGN: Population-based prospective cohort study with 18 years of follow-up. METHODS: A linkage between a Norwegian population-based study (Nord-Trøndelag health study) and the Cause of Death Registry at Statistics Norway. Exercise amount and intensity were measured at baseline (1984-1986) in 2137 men and 1367 women with CHD. RESULTS: During 18 years of follow-up, 1741 (81.6%) men and 1100 (80.5%) women died. Compared with the reference category (no activity), one weekly exercise session was associated with a lower all-cause mortality, both in men (relative risk 0.80, 95% confidence interval 0.68-0.94) and women (relative risk 0.68, 95% confidence interval 0.55-0.83). This inverse association became stronger with increasing frequency (P< or =0.001 for men and women). Those who reported moderate or high-intensity exercise had a somewhat lower risk of death than those who exercised with low intensity. CONCLUSION: Exercise training reduced all-cause and cardiovascular mortality in men and women with CHD. This study adds significantly to the sparse literature regarding prospective data on physical activity, exercise intensity and mortality in CHD patients.
Authors: Antonio Alberto Lopes; Brett Lantz; Hal Morgenstern; Mia Wang; Brian A Bieber; Brenda W Gillespie; Yun Li; Patricia Painter; Stefan H Jacobson; Hugh C Rayner; Donna L Mapes; Raymond C Vanholder; Takeshi Hasegawa; Bruce M Robinson; Ronald L Pisoni Journal: Clin J Am Soc Nephrol Date: 2014-10-02 Impact factor: 8.237
Authors: Sara Higueras-Fresnillo; Verónica Cabanas-Sánchez; Esther García-Esquinas; Fernando Rodríguez-Artalejo; David Martinez-Gomez Journal: Qual Life Res Date: 2018-09-11 Impact factor: 4.147
Authors: Wolfgang Kemmler; Michael Scharf; Michael Lell; Carina Petrasek; Simon von Stengel Journal: Biomed Res Int Date: 2014-03-11 Impact factor: 3.411
Authors: Adam A Lucero; Danielle M Lambrick; James A Faulkner; Simon Fryer; Michael A Tarrant; Melanie Poudevigne; Michelle A Williams; Lee Stoner Journal: Adv Prev Med Date: 2014-02-06