Literature DB >> 18779709

Radial optic neurotomy for central retinal vein occlusion: results of the Pan-American Collaborative Retina Study Group (PACORES).

J Fernando Arevalo1, Reinaldo A Garcia, Lihteh Wu, Francisco J Rodriguez, Jose Dalma-Weiszhausz, Hugo Quiroz-Mercado, Virgilio Morales-Canton, Jose A Roca, Maria H Berrocal, Federico Graue-Wiechers, Violeta Robledo.   

Abstract

OBJECTIVE: To evaluate the complications after radial optic neurotomy (RON) for central retinal vein occlusion (CRVO).
METHODS: Seventy-three consecutive patients (73 eyes) with CRVO who were treated with RON participated in a retrospective, uncontrolled, interventional, multicenter case series at 7 institutions from 6 countries.
RESULTS: In the ischemic CRVO group (n = 53), 32% of eyes had an improvement in best-corrected visual acuity (BCVA) (mean, 5.5 lines), 35.8% had worse BCVA (mean, 6.4 lines), and 32% had BCVA that remained the same after RON. In the nonischemic CRVO group (n = 20), 50% of eyes had an improvement in BCVA (mean, 6.5 lines), 15% had worse BCVA (mean, 4.3 lines), and 35% had BCVA that remained the same after RON. Complications occurred in 71.2% of cases, including cataract in 17 eyes (23.2%), vitreous hemorrhage in 16 eyes (20.5%), persistent macular edema in 15 eyes (20.5%), neovascular glaucoma in 7 eyes (9.5%), anterior segment neovascularization in 5 eyes (6.8%), retinal detachment in 3 eyes (4.1%), and phthisis bulbi, choroidovitreal neovascularization, central retinal artery perforation, and optic nerve atrophy in 1 eye (1.3%) each.
CONCLUSIONS: RON may improve visual acuity in some eyes with CRVO, but complications are common. In our series, surgery by itself did not seem to improve the outcome of CRVO when compared with its natural history.

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Mesh:

Year:  2008        PMID: 18779709     DOI: 10.1097/IAE.0b013e3181744153

Source DB:  PubMed          Journal:  Retina        ISSN: 0275-004X            Impact factor:   4.256


  12 in total

Review 1.  Anti-vascular endothelial growth factor for macular edema secondary to central retinal vein occlusion.

Authors:  Tasanee Braithwaite; Afshan A Nanji; Paul B Greenberg
Journal:  Cochrane Database Syst Rev       Date:  2010-10-06

2.  Radial optic neurotomy in treating central retinal vein occlusion: a Meta-analysis.

Authors:  Zhen-Na Chen; Yan Shao; Xiao-Rong Li
Journal:  Int J Ophthalmol       Date:  2016-06-18       Impact factor: 1.779

3.  Comparison of anti-vascular endothelial growth factors, laser treatments and a combination of the both for treatment of central retinal vein occlusion.

Authors:  Yoav Y Pikkel; Adi Sharabi-Nov; Itzchak Beiran; Joseph Pikkel
Journal:  Int J Ophthalmol       Date:  2016-03-18       Impact factor: 1.779

Review 4.  Anti-vascular endothelial growth factor for macular oedema secondary to central retinal vein occlusion.

Authors:  Tasanee Braithwaite; Afshan A Nanji; Kristina Lindsley; Paul B Greenberg
Journal:  Cochrane Database Syst Rev       Date:  2014-05-01

5.  A prospective, randomised, multicenter trial for surgical treatment of central retinal vein occlusion: results of the Radial Optic Neurotomy for Central Vein Occlusion (ROVO) study group.

Authors:  Tina Aggermann; Simon Brunner; Ilse Krebs; Paulina Haas; Irene Womastek; Werner Brannath; Susanne Binder
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-09-08       Impact factor: 3.117

6.  Effects of apelin and vascular endothelial growth factor on central retinal vein occlusion in monkey eyes intravitreally injected with bevacizumab: a preliminary study.

Authors:  Tong Zhao; Qiang Lu; Yong Tao; Xiao-Ying Liang; Kai Wang; Yan-Rong Jiang
Journal:  Mol Vis       Date:  2011-04-27       Impact factor: 2.367

7.  Therapeutic benefit of radial optic neurotomy in a rat model of glaucoma.

Authors:  Nicolás Belforte; Pablo H Sande; Nuria de Zavalía; Damián Dorfman; Ruth E Rosenstein
Journal:  PLoS One       Date:  2012-03-29       Impact factor: 3.240

8.  Practical management of retinal vein occlusions.

Authors:  Carlo La Spina; Umberto De Benedetto; Maurizio Battaglia Parodi; Gabriel Coscas; Francesco Bandello
Journal:  Ophthalmol Ther       Date:  2012-08-09

9.  Radial optic neurotomy for central retinal vein occlusion.

Authors:  Ali-Reza Ramezani
Journal:  J Ophthalmic Vis Res       Date:  2009-04

10.  Bevacizumab for CRVO Associated CME: Effect of Timing and Frequency of Injections on Final Visual Outcome.

Authors:  Joseph Pikkel; Otzem Chassid; Yumna Busool; Ward Srour; Adi Sharabi-Nov; Itzchak Beiran
Journal:  J Ophthalmol       Date:  2013-12-29       Impact factor: 1.909

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