Literature DB >> 18778959

Management of motor problems in cerebral palsy: a critical update for the clinician.

Antigone S Papavasiliou1.   

Abstract

Currently there is no specific treatment for the brain insults leading to motor dysfunction in cerebral palsy. The available symptomatic therapeutic options place cerebral palsy among the costliest chronic childhood conditions. Therefore, it is necessary to make well-informed decisions in an effort to match cost-effectiveness with patient and family needs. This presentation aims to analyze the efficacy of rehabilitation therapy, orthoses, oral medications, botulinum toxin, intrathecal baclofen, complementary or alternative treatments and discuss guidelines for a goal oriented approach. Despite insufficient reporting of trials, physiotherapy has shifted from traditional to goal oriented approaches, based on principles of motor learning, strength and fitness training. Correct choice and use of orthoses is stressed, yet evidence from primary studies is limited. Pharmacological treatments of spasticity (oral agents, botulinum toxin, intrathecal baclofen) may be alternatives or supplements to orthopaedic surgery. There is evidence that botulinum toxin combined with conservative treatments reduces the number of complex orthopaedic interventions. Intrathecal baclofen effectively reduces spasticity; criteria describing the ideal candidate are needed. Complementary or alternative treatment use is widespread; research needs to determine what factors make these modalities desirable and effective in cerebral palsy. It is concluded that the introduction of new therapies facilitates an individualized management plan. Multimodal treatment is optimized with a multidisciplinary team. Outcome measurement according to the World Health Organization's new International Classification of Functioning, Disability and Health is emphasized.

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Year:  2008        PMID: 18778959     DOI: 10.1016/j.ejpn.2008.07.009

Source DB:  PubMed          Journal:  Eur J Paediatr Neurol        ISSN: 1090-3798            Impact factor:   3.140


  23 in total

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Journal:  Mol Genet Metab       Date:  2017-08-20       Impact factor: 4.797

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Journal:  Mol Genet Metab       Date:  2018-01-31       Impact factor: 4.797

6.  Change in basic motor abilities, quality of movement and everyday activities following intensive, goal-directed, activity-focused physiotherapy in a group setting for children with cerebral palsy.

Authors:  Anne Brit Sorsdahl; Rolf Moe-Nilssen; Helga K Kaale; Jannike Rieber; Liv Inger Strand
Journal:  BMC Pediatr       Date:  2010-04-27       Impact factor: 2.125

7.  Reduced short term adaptation to robot generated dynamic environment in children affected by Cerebral Palsy.

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Journal:  J Neuroeng Rehabil       Date:  2011-05-21       Impact factor: 4.262

8.  Factors related to psychosocial quality of life for children with cerebral palsy.

Authors:  D W Tessier; J L Hefner; A Newmeyer
Journal:  Int J Pediatr       Date:  2014-01-23

9.  Safety of botulinum toxin A in children and adolescents with cerebral palsy in a pragmatic setting.

Authors:  Antigone S Papavasiliou; Irene Nikaina; Katerina Foska; Panagiotis Bouros; George Mitsou; Constantine Filiopoulos
Journal:  Toxins (Basel)       Date:  2013-03-12       Impact factor: 4.546

10.  Comparison of Quality of Life Following Single- Event Multilevel Surgery (SEMLS) Using Bandaging and Casting Immobilization Methods in Cerebral Palsy Children.

Authors:  Esmaeil Sadeghi; Ali Asghar Jamebozorgi; Mohamad Qoreishy; Melika Kangarani Farahani
Journal:  Iran J Child Neurol       Date:  2021
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