Protracted fever with cellulitis-like reaction in pneumococcal polysaccharide-vaccinated children.

Side effects of the 23-valent pneumococcal polysaccharide vaccine (PPV23) are regarded as mild and uncommon in adults. In our clinical experience, however, protracted fever with a cellulitis-like reaction after PPV23 vaccination is not rare in pediatric patients. We reviewed the records of 17 children with those clinical findings after PPV23 vaccination.