| Literature DB >> 18776583 |
Luca De Stefano1, Edoardo De Tommasi, Ilaria Rea, Lucia Rotiroti, Luca Giangrande, Giorgia Oliviero, Nicola Borbone, Aldo Galeone, Gennaro Piccialli.
Abstract
A solid phase oligonucleotide (ON) synthesis on porous silicon (PSi) chip is presented. The prepared Si-OH surface were analyzed by FT-IR and the OH functions were quantified by reaction with 3'-phosphoramidite nucleotide building block. Short ONs were synthesized on the chip surface and the coupling yields evaluated.Entities:
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Year: 2008 PMID： 18776583 DOI： 10.1093/nass/nrn364
Source DB: PubMed Journal: Nucleic Acids Symp Ser (Oxf) ISSN： 0261-3166