Literature DB >> 18774864

Frajunolides E-K, briarane diterpenes from Junceella fragilis.

Chia-Ching Liaw1, Ya-Ching Shen, Yun-Sheng Lin, Tsong-Long Hwang, Yao-Haur Kuo, Ashraf Taha Khalil.   

Abstract

Chemical investigation of the gorgonian octocoral Junceella fragilis, collected in Taiwan, resulted in the isolation of seven new briarane-type diterpenes, frajunolides E-K (1-7), in addition to 14 known briaranes, praelolide, junceellin, junceellolides A-E, and K, 11a,20a-epoxy-4-deacetoxyjunceelolide D, umbraculolide A, junceellonoid A, and juncins Y, Z, and ZI, as well as ergosterol peroxide. The structures of 1-7 were determined by analysis of HRESIMS and 2D NMR spectroscopic data. Cytotoxicity and in vitro anti-inflammatory activities of compounds 1-7 were also evaluated.

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Year:  2008        PMID： 18774864     DOI： 10.1021/np800126f

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  16 in total

1.  Frajunolides L-O, four new 8-Hydroxybriarane diterpenoids from the Gorgonian Junceella fragilis.

Authors:  Chia-Ching Liaw; Yao-Haur Kuo; Yun-Sheng Lin; Tsong-Long Hwang; Ya-Ching Shen
Journal:  Mar Drugs       Date:  2011-09-02       Impact factor: 6.085

Review 2.  Natural product chemistry of gorgonian corals of genus Junceella--part II.

Authors:  Yang-Chang Wu; Jui-Hsin Su; Tai-Ting Chou; Yin-Pin Cheng; Ching-Feng Weng; Chia-Hung Lee; Lee-Shing Fang; Wei-Hsien Wang; Jan-Jung Li; Mei-Chin Lu; Jimmy Kuo; Jyh-Horng Sheu; Ping-Jyun Sung
Journal:  Mar Drugs       Date:  2011-12-19       Impact factor: 6.085

3.  New Briarane diterpenoids from the gorgonian coral Junceella juncea.

Authors:  Jiun-Yang Chang; Chia-Ching Liaw; Ahmed Eid Fazary; Tsong-Long Hwang; Ya-Ching Shen
Journal:  Mar Drugs       Date:  2012-06-07       Impact factor: 6.085

4.  Anti-Inflammatory and Analgesic Effects of the Marine-Derived Compound Excavatolide B Isolated from the Culture-Type Formosan Gorgonian Briareum excavatum.

Authors:  Yen-You Lin; Sung-Chun Lin; Chien-Wei Feng; Pei-Chin Chen; Yin-Di Su; Chi-Min Li; San-Nan Yang; Yen-Hsuan Jean; Ping-Jyun Sung; Chang-Yih Duh; Zhi-Hong Wen
Journal:  Mar Drugs       Date:  2015-04-27       Impact factor: 5.118

Review 5.  Anti-inflammatory activities of natural products isolated from soft corals of Taiwan between 2008 and 2012.

Authors:  Wen-Chi Wei; Ping-Jyun Sung; Chang-Yih Duh; Bo-Wei Chen; Jyh-Horng Sheu; Ning-Sun Yang
Journal:  Mar Drugs       Date:  2013-10-23       Impact factor: 5.118

6.  New briarane diterpenoids from Taiwanese soft coral Briareum violacea.

Authors:  Chia-Ching Liaw; Yuan-Bin Cheng; Yun-Sheng Lin; Yao-Haur Kuo; Tsong-Long Hwang; Ya-Ching Shen
Journal:  Mar Drugs       Date:  2014-08-22       Impact factor: 5.118

7.  Briarane diterpenoids from the gorgonian Dichotella gemmacea.

Authors:  Ming-Ping La; Jiao Li; Cui Li; Hua Tang; Bao-Shu Liu; Peng Sun; Chun-Lin Zhuang; Tie-Jun Li; Wen Zhang
Journal:  Mar Drugs       Date:  2014-12-18       Impact factor: 5.118

Review 8.  Marine Natural Product Inhibitors of Neutrophil-Associated Inflammation.

Authors:  Chun-Yu Chen; Yung-Fong Tsai; Wen-Yi Chang; Shun-Chin Yang; Tsong-Long Hwang
Journal:  Mar Drugs       Date:  2016-07-26       Impact factor: 5.118

9.  Four new briarane diterpenoids from Taiwanese gorgonian Junceella fragilis.

Authors:  Chia-Ching Liaw; Yu-Chi Lin; Yun-Sheng Lin; Chung-Hsiung Chen; Tsong-Long Hwang; Ya-Ching Shen
Journal:  Mar Drugs       Date:  2013-06-10       Impact factor: 5.118

Review 10.  Marine Diterpenoids as Potential Anti-Inflammatory Agents.

Authors:  Yisett González; Daniel Torres-Mendoza; Gillian E Jones; Patricia L Fernandez
Journal:  Mediators Inflamm       Date:  2015-10-11       Impact factor: 4.711
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