BACKGROUND:Long-term home mechanical ventilation (HMV) is usually initiated in hospital. Admission to hospital has resource implications and may not be reimbursable in some healthcare systems. METHODS:Twenty-eight stable neuromuscular and chest wall disease patients with nocturnal hypoventilation (transcutaneous carbon dioxide (TcCO(2) >6.5 kPa), were randomised to start HMV either as an outpatient (n=14, age range 12-62 years) or inpatient (n=14, age range 14-73 years). We compared effects of HMV on nocturnal and diurnal arterial blood gas tensions, ventilator compliance, healthcare professional (HCP) contact time, and time in hospital. RESULTS: Improvements in nocturnal arterial oxygen saturation (SaO(2)) and daytime PaO(2) were equivalent in both groups. Peak nocturnal TcCO(2), improved in both groups; % time TcCO(2) >6.5 kPa fell in the inpatient group and daytime PaCO(2) decreased significantly (p<0.05) in the outpatient group. The mean (SD) inpatient stay was 3.8 (1.0) days, and the outpatient attendance sessions 1.2 (0.4). HCP contact time including telephone calls was: inpatient 177 (99) min; outpatient 188 (60) min (p=not significant); 2 month ventilator compliance was: inpatient 4.32 (7); outpatient 3.92 (8) (p=not significant) hours per night. CONCLUSION: Outpatient initiation of HMV is feasible with equivalent outcome in the outpatient and the inpatient groups.
RCT Entities:
BACKGROUND: Long-term home mechanical ventilation (HMV) is usually initiated in hospital. Admission to hospital has resource implications and may not be reimbursable in some healthcare systems. METHODS: Twenty-eight stable neuromuscular and chest wall disease patients with nocturnal hypoventilation (transcutaneous carbon dioxide (TcCO(2) >6.5 kPa), were randomised to start HMV either as an outpatient (n=14, age range 12-62 years) or inpatient (n=14, age range 14-73 years). We compared effects of HMV on nocturnal and diurnal arterial blood gas tensions, ventilator compliance, healthcare professional (HCP) contact time, and time in hospital. RESULTS: Improvements in nocturnal arterial oxygen saturation (SaO(2)) and daytime PaO(2) were equivalent in both groups. Peak nocturnal TcCO(2), improved in both groups; % time TcCO(2) >6.5 kPa fell in the inpatient group and daytime PaCO(2) decreased significantly (p<0.05) in the outpatient group. The mean (SD) inpatient stay was 3.8 (1.0) days, and the outpatient attendance sessions 1.2 (0.4). HCP contact time including telephone calls was: inpatient 177 (99) min; outpatient 188 (60) min (p=not significant); 2 month ventilator compliance was: inpatient 4.32 (7); outpatient 3.92 (8) (p=not significant) hours per night. CONCLUSION:Outpatient initiation of HMV is feasible with equivalent outcome in the outpatient and the inpatient groups.
Authors: Richard B Berry; Alejandro Chediak; Lee K Brown; Jonathan Finder; David Gozal; Conrad Iber; Clete A Kushida; Timothy Morgenthaler; James A Rowley; Sally L Davidson-Ward Journal: J Clin Sleep Med Date: 2010-10-15 Impact factor: 4.062
Authors: Ha Trang; Jean-François Brunet; Hermann Rohrer; Jorge Gallego; Jeanne Amiel; Tiziana Bachetti; Kenneth H Fischbeck; Thomas Similowski; Christian Straus; Isabella Ceccherini; Debra E Weese-Mayer; Matthias Frerick; Katarzyna Bieganowska; Linda Middleton; Francesco Morandi; Giancarlo Ottonello Journal: Orphanet J Rare Dis Date: 2014-12-05 Impact factor: 4.123
Authors: Stephanie K Mansell; Steven Cutts; Isobel Hackney; Martin J Wood; Kevin Hawksworth; Dean D Creer; Cherry Kilbride; Swapna Mandal Journal: BMJ Open Respir Res Date: 2018-03-03