| Literature DB >> 18774148 |
Zhanzhong Zhao1, Jian Wang, Peihong Liu, Suhua Zhang, Jianpei Gong, Xiqin Huang, Bin Li, Feiqun Xue.
Abstract
The effects of nutritional components and submerged culture conditions on colony-forming unit (CFU) counts by Streptococcus suis serotype 2 strain HA9801 in flask culture was investigated, and the optimal medium and cultivation conditions was confirmed by using a 50l bioreactor. The LD(50) values of HA9801 in pigs before and after fermentation were 1.8 x 10(7)CFU, which indicated that the virulence of HA9801 was very stable in the fermentation process. In addition, an experimental model that closely mimics naturally occurring disease in conventional pigs was established.Entities:
Mesh：
Year: 2008 PMID： 18774148 DOI： 10.1016/j.rvsc.2008.07.012
Source DB: PubMed Journal: Res Vet Sci ISSN： 0034-5288 Impact factor: 2.534