Literature DB >> 18774134

Low occurrence of ischemic heart disease among Inuit around 1963 suggested from ECG among 1851 East Greenland Inuit.

Marie Kjaergaard1, Stig Andersen, Mads Holten, Gert Mulvad, Jens Jørgen Kjaergaard.   

Abstract

BACKGROUND: The prevalence of coronary heart disease among Greenland Inuit today is similar to that of western populations. The cardiovascular risk profile among Inuit has changed over the past four decades with the introduction of a western life style. An unaltered prevalence of coronary heart disease has been proposed, but no pre-westernisation data exist. AIM: To describe pre-westernisation prevalence of coronary heart disease among East Greenland Inuit.
DESIGN: A population study of 1851 Inuit living in East Greenland was conducted in 1962-1964. It included ECG, cardiac auscultation and recording of symptoms. ECGs were evaluated for ischemic signs, arrhythmia, hypertrophy, and conduction abnormalities.
RESULTS: The participation rate was 97%. A12-lead ECG was performed in 181 adults, including 65% of men aged 40 years and above. Hypertrophy was seen in 15% and peaked in 30-39 year olds. Pathological conduction disturbances were seen in 4% and 1% had ischemic signs. The age-standardised prevalence of ischemic ECG findings was 5.5%. Abnormal ECG findings did not correlate with pathologic findings on cardiac auscultation or symptoms related to heart disease.
CONCLUSIONS: Hypertrophy peaked among 30 years olds. Ischemic ECG findings were present in East Greenland Inuit before westernisation, the prevalence clearly lower than today.

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Mesh:

Year:  2008        PMID: 18774134     DOI: 10.1016/j.atherosclerosis.2008.07.027

Source DB:  PubMed          Journal:  Atherosclerosis        ISSN: 0021-9150            Impact factor:   5.162


  5 in total

1.  Relation between methylmercury exposure and plasma paraoxonase activity in inuit adults from Nunavik.

Authors:  Pierre Ayotte; Antoine Carrier; Nathalie Ouellet; Véronique Boiteau; Belkacem Abdous; Elhadji Anassour Laouan Sidi; Marie-Ludivine Château-Degat; Éric Dewailly
Journal:  Environ Health Perspect       Date:  2011-05-04       Impact factor: 9.031

2.  The influence of persistent organic pollutants in the traditional Inuit diet on markers of inflammation.

Authors:  L K Schæbel; E C Bonefeld-Jørgensen; H Vestergaard; S Andersen
Journal:  PLoS One       Date:  2017-05-19       Impact factor: 3.240

3.  The prevalence of atrial fibrillation in Greenland: a register-based cross-sectional study based on disease classifications and prescriptions of oral anticoagulants.

Authors:  N Albertsen; S Riahi; M L Pedersen; N Skovgaard; S Andersen
Journal:  Int J Circumpolar Health       Date:  2022-12       Impact factor: 1.228

Review 4.  Raised BMI cut-off for overweight in Greenland Inuit--a review.

Authors:  Stig Andersen; Karsten Fleischer Rex; Paneeraq Noahsen; Hans Christian Florian Sørensen; Gert Mulvad; Peter Laurberg
Journal:  Int J Circumpolar Health       Date:  2013-08-05       Impact factor: 1.228

5.  Vitamin D-rich marine Inuit diet and markers of inflammation - a population-based survey in Greenland.

Authors:  L K Schæbel; E C Bonefeld-Jørgensen; P Laurberg; H Vestergaard; S Andersen
Journal:  J Nutr Sci       Date:  2015-12-16
  5 in total

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