Literature DB >> 187729

Reactivation of herpes simplex virus infection by ultraviolet light and possible involvement of prostaglandins.

W A Blyth, T J Hill, H J Field, D A Harbour.   

Abstract

Herpes simplex infection in the mouse ear was used to investigate whether various treatments would reactivate the disease. Immunosuppressive drugs failed to induce clinical signs of reactivation but irradiation of the skin of the originally infected ear with ultraviolet light or injection of prostaglandin E2 or PBSA into this site, caused reactivation of infection. This was detected by the appearance of infectious virus in the skin 2 to 3 days after these treatments. The results are discussed in relation to the mechanism of herpes reactivation in man.

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Year:  1976        PMID： 187729     DOI： 10.1099/0022-1317-33-3-547

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  32 in total

1.  Quantitative analysis of herpes simplex virus reactivation in vivo demonstrates that reactivation in the nervous system is not inhibited at early times postinoculation.

Authors:  N M Sawtell
Journal:  J Virol       Date:  2003-04       Impact factor: 5.103

2.  Herpes simplex latency and the eye.

Authors:  J McGill
Journal:  Br J Ophthalmol       Date:  1991-11       Impact factor: 4.638

3.  The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency.

Authors:  D A Leib; K C Nadeau; S A Rundle; P A Schaffer
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

4.  The effect of ultraviolet light on primary herpes simplex virus infection in the mouse.

Authors:  D A Harbour; T J Hill; W A Blyth
Journal:  Arch Virol       Date:  1977       Impact factor: 2.574

Review 5.  Herpes simplex virus ocular infections: current concepts of acute, latent and reactivated disease.

Authors:  D Pavan-Langston
Journal:  Trans Am Ophthalmol Soc       Date:  1990

6.  The role of free radical scavengers, inhibitors of prostaglandin synthesis, and hypomethylating agents in reactivation of latent herpes simplex virus.

Authors:  S Sienko; A M Eis-Hübinger; K E Schneweis
Journal:  Med Microbiol Immunol       Date:  1991       Impact factor: 3.402

7.  Reactivation of latent herpes simplex virus infection of the autonomic nervous system by postganglionic neurectomy.

Authors:  R W Price; J Schmitz
Journal:  Infect Immun       Date:  1978-02       Impact factor: 3.441

8.  Herpes simplex virus gene expression in neurons: viral DNA synthesis is a critical regulatory event in the branch point between the lytic and latent pathways.

Authors:  P F Nichol; J Y Chang; E M Johnson; P D Olivo
Journal:  J Virol       Date:  1996-08       Impact factor: 5.103

Review 9.  Role of epidermal Langerhans cells in viral infections.

Authors:  E Sprecher; Y Becker
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

Review 10.  Persistence in herpes simplex virus infections.

Authors:  M Longson
Journal:  Postgrad Med J       Date:  1978-09       Impact factor: 2.401
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