Literature DB >> 18772817

[Ocular ochronosis. A case report].

N Ben Rayana1, N Chahed, S Khochtali, M Ghorbel, R Hamdi, M Rouis, I Bouajina, F Ben Hadj Hamida.   

Abstract

Ochronosis or alkaptonuria is a rare inherited disease. It is characterized by the deposition of dark pigments in collagen-rich tissues, which leads to clinical manifestations such as arthropathy. The ochronotic pigment can be found in the sclera, the conjunctiva, and the limbic cornea. Vision is usually not affected. We report the case of 47-year-old patient who complained of lower back pain. Ophthalmologic examination showed dark pigments in the conjunctiva. The increased levels of homogentisic acid in urine confirmed the diagnosis of ochronosis.

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Year:  2008        PMID: 18772817

Source DB:  PubMed          Journal:  J Fr Ophtalmol        ISSN: 0181-5512            Impact factor:   0.818


  2 in total

Review 1.  On the ocular findings in ochronosis: a systematic review of literature.

Authors:  Moritz Lindner; Thomas Bertelmann
Journal:  BMC Ophthalmol       Date:  2014-01-30       Impact factor: 2.209

2.  Alkaptonuria diagnosed in a 4-month-old baby girl: a case report.

Authors:  Asok K Datta; Syamali Mandal; Anindya Dasgupta; Tarun K Ghosh
Journal:  Cases J       Date:  2008-11-13
  2 in total

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