BACKGROUND: We examined relationships between visceral fat amount and alterations in serum fatty acid composition, both of which represent critical factors in the development of metabolic syndrome. METHODS: Correlations were analyzed between visceral fat thickness as measured by ultrasonography and proportions of individual fatty acids in 21 normal-weight and 24 overweight Japanese men. RESULTS: Significant associations were identified in overweight subjects. Visceral fat thickness displayed positive correlations to levels of palmitic acid and saturated fatty acids (r=0.475, P<0.05 and r=0.545, P<0.01, respectively); and negative correlations to levels of linoleic acid and polyunsaturated fatty acids (r=-0.513, P<0.05 and r=-0.428, P<0.05, respectively). Visceral fat thickness was also correlated with estimated desaturase activities, with positive correlations to Delta9- and Delta6-desaturase activities and negative correlations to Delta5-desaturase activity (r=0.580, P<0.01, r=0.669, P<0.01 and r=-0.559, P<0.01, respectively). No significant associations were identified in normal-weight subjects. CONCLUSIONS: Significant associations between visceral fat amount and alterations in serum fatty acid composition were identified, but only in overweight individuals.
BACKGROUND: We examined relationships between visceral fat amount and alterations in serum fatty acid composition, both of which represent critical factors in the development of metabolic syndrome. METHODS: Correlations were analyzed between visceral fat thickness as measured by ultrasonography and proportions of individual fatty acids in 21 normal-weight and 24 overweight Japanese men. RESULTS: Significant associations were identified in overweight subjects. Visceral fat thickness displayed positive correlations to levels of palmitic acid and saturated fatty acids (r=0.475, P<0.05 and r=0.545, P<0.01, respectively); and negative correlations to levels of linoleic acid and polyunsaturated fatty acids (r=-0.513, P<0.05 and r=-0.428, P<0.05, respectively). Visceral fat thickness was also correlated with estimated desaturase activities, with positive correlations to Delta9- and Delta6-desaturase activities and negative correlations to Delta5-desaturase activity (r=0.580, P<0.01, r=0.669, P<0.01 and r=-0.559, P<0.01, respectively). No significant associations were identified in normal-weight subjects. CONCLUSIONS: Significant associations between visceral fat amount and alterations in serum fatty acid composition were identified, but only in overweight individuals.
Authors: Laura E Tomedi; Chung-Chou H Chang; P K Newby; Rhobert W Evans; James F Luther; Katherine L Wisner; Lisa M Bodnar Journal: Public Health Nutr Date: 2013-03-25 Impact factor: 4.022
Authors: Fredrik Rosqvist; Helena Bjermo; Joel Kullberg; Lars Johansson; Karl Michaëlsson; Håkan Ahlström; Lars Lind; Ulf Risérus Journal: Lipids Health Dis Date: 2017-04-04 Impact factor: 3.876
Authors: Aleksandra Jelena Vidakovic; Vincent W V Jaddoe; Olta Gishti; Janine F Felix; Michelle A Williams; Albert Hofman; Hans Demmelmair; Berthold Koletzko; Henning Tiemeier; Romy Gaillard Journal: Eur J Epidemiol Date: 2015-12-14 Impact factor: 8.082
Authors: Young Ju Lee; Ayoung Lee; Hye Jin Yoo; Minjoo Kim; Minkyung Kim; Sun Ha Jee; Dong Yeob Shin; Jong Ho Lee Journal: Nutr J Date: 2018-02-22 Impact factor: 3.271
Authors: Kamalita Pertiwi; Leanne K Küpers; Johanna M Geleijnse; Peter L Zock; Anne J Wanders; Herculina S Kruger; Tertia van Zyl; Iolanthé M Kruger; Cornelius M Smuts Journal: Lipids Health Dis Date: 2020-06-16 Impact factor: 3.876