Literature DB >> 1877058

Preoperative assessment of the likelihood of infection of the lower respiratory tract after cardiac surgery.

T Carrel1, E R Schmid, L von Segesser, M Vogt, M Turina.   

Abstract

Lower-respiratory-tract infections are among the most frequent complications observed in the intensive care unit, leading to delayed postoperative recovery time and increased costs and mortality. We have tried to evaluate the prognostic value of perioperative bacteriology of tracheal aspirates in assessing the risk of such complications. In a prospective study aspirates of 100 patients undergoing cardiac surgery were taken immediately after intubation and were analysed for microorganisms by Gram-stain and microbiological cultures using standard procedures. All patients received perioperative antibiotic prophylaxis with a single dose of 2 g ceftriaxone intravenously. From 26 patients with bacteriologically positive tracheal secretion, 8 (30.7%) developed lower respiratory tract infection whereas only 1 of 72 patients (1.4%) with negative bacteriological results developed this complication. Smoking (p less than 0.01) and abnormal preoperative lung function (p less than 0.01) were significantly more frequent in patients developing postoperative pneumonia. Regarding the results of this study, the risk of developing pulmonary infection in the early postoperative course after cardiac surgery can be estimated from the tracheal aspirates.

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Year:  1991        PMID: 1877058     DOI: 10.1055/s-2007-1013938

Source DB:  PubMed          Journal:  Thorac Cardiovasc Surg        ISSN: 0171-6425            Impact factor:   1.827


  6 in total

1.  In vivo measurement of levofloxacin penetration into lung tissue after cardiac surgery.

Authors:  Doris Hutschala; Keso Skhirtladze; Andreas Zuckermann; Wilfried Wisser; Peter Jaksch; Bernhard Xaver Mayer-Helm; Heinz Burgmann; Ernst Wolner; Markus Müller; Edda M Tschernko
Journal:  Antimicrob Agents Chemother       Date:  2005-12       Impact factor: 5.191

Review 2.  Role of microdialysis in pharmacokinetics and pharmacodynamics: current status and future directions.

Authors:  Francine Johansson Azeredo; Teresa Dalla Costa; Hartmut Derendorf
Journal:  Clin Pharmacokinet       Date:  2014-03       Impact factor: 6.447

3.  ["Single-shot" antibiotic prophylaxis in thoracic surgery; reduction of the postoperative infection rate].

Authors:  D J Frey; A K Reichmann; H Mauch; D Kaiser
Journal:  Infection       Date:  1993       Impact factor: 3.553

4.  The impact of perioperative atelectasis on antibiotic penetration into lung tissue: an in vivo microdialysis study.

Authors:  Doris Hutschala; Christian Kinstner; Keso Skhirtladze; Bernhard-Xaver Mayer-Helm; Markus Zeitlinger; Wilfried Wisser; Markus Müller; Edda Tschernko
Journal:  Intensive Care Med       Date:  2008-05-14       Impact factor: 17.440

5.  Normal Reference Interval of WBC Count After On - Pump Coronary Artery Bypass Graft; When Values Could Be Misleading.

Authors:  Fardin Yousefshahi; Mohammadali Boroumand; Katayoun Haryalchi; Jayran Zebardast; Azin Ghajar; Ehsan Bastan Hagh
Journal:  Anesth Pain Med       Date:  2018-06-21

6.  Ventilator-associated pneumonia in patients undergoing major heart surgery: an incidence study in Europe.

Authors:  Javier Hortal; Patricia Muñoz; Gregorio Cuerpo; Hector Litvan; Peter M Rosseel; Emilio Bouza
Journal:  Crit Care       Date:  2009-05-22       Impact factor: 9.097

  6 in total

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