The response of the Harderian gland of the fowl to antigen given by the ocular route. II. Antibody production.

After ocular administration to young chickens of sheep erythrocytes (SRBC), Newcastle disease virus (NDV), infectious bronchitis virus (IBV) or Mycoplasma gallisepticum, homologous antibody was detected in serum and in saline extracts of Harderian glands. Parenteral immunisation with SRBC or NDV stimulated moderately high serum antibody titres but did not evoke a measurable antibody response by the Harderian gland.