Literature DB >> 18769454

Miltefosine inhibits human mast cell activation and mediator release both in vitro and in vivo.

Karsten Weller, Metin Artuc, Gary Jennings, Tim Friedrichson, Sven Guhl, Rosaly V dos Santos, Cathleen Sünder, Torsten Zuberbier, Marcus Maurer.   

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Year:  2008        PMID： 18769454     DOI： 10.1038/jid.2008.248

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


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  6 in total

1.  A Combination of Screening and Computational Approaches for the Identification of Novel Compounds That Decrease Mast Cell Degranulation.

Authors:  Marisa P McShane; Tim Friedrichson; Angelika Giner; Felix Meyenhofer; Rico Barsacchi; Marc Bickle; Marino Zerial
Journal:  J Biomol Screen       Date:  2015-04-02

2.  Miltefosine increases macrophage cholesterol release and inhibits NLRP3-inflammasome assembly and IL-1β release.

Authors:  Amanda J Iacano; Harvey Lewis; Jennie E Hazen; Heather Andro; Jonathan D Smith; Kailash Gulshan
Journal:  Sci Rep       Date:  2019-07-31       Impact factor: 4.379

3.  Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms.

Authors:  Sara Botschuijver; Sophie A van Diest; Isabelle A M van Thiel; Rafael S Saia; Anne S Strik; Zhumei Yu; Daniele Maria-Ferreira; Olaf Welting; Daniel Keszthelyi; Gary Jennings; Sigrid E M Heinsbroek; Ronald P Oude Elferink; Frank H J Schuren; Wouter J de Jonge; René M van den Wijngaard
Journal:  Sci Rep       Date:  2019-08-29       Impact factor: 4.379

Review 4.  Pharmacological treatment options for mast cell activation disease.

Authors:  Gerhard J Molderings; Britta Haenisch; Stefan Brettner; Jürgen Homann; Markus Menzen; Franz Ludwig Dumoulin; Jens Panse; Joseph Butterfield; Lawrence B Afrin
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2016-04-30       Impact factor: 3.000

5.  Mast Cell Activation and Microtubule Organization Are Modulated by Miltefosine Through Protein Kinase C Inhibition.

Authors:  Zuzana Rubíková; Vadym Sulimenko; Tomáš Paulenda; Pavel Dráber
Journal:  Front Immunol       Date:  2018-07-09       Impact factor: 7.561

6.  The anti-parasitic drug miltefosine suppresses activation of human eosinophils and ameliorates allergic inflammation in mice.

Authors:  Eva Knuplez; Melanie Kienzl; Athina Trakaki; Rudolf Schicho; Akos Heinemann; Eva M Sturm; Gunther Marsche
Journal:  Br J Pharmacol       Date:  2021-02-02       Impact factor: 9.473
  6 in total

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