Literature DB >> 18766395

Obstructive sleep apnea and erectile dysfunction: still a neglected risk factor?

Nikolaos Zias1, Vishnu Bezwada, Sean Gilman, Alexandra Chroneou.   

Abstract

INTRODUCTION: Erectile dysfunction (ED) is a well-known entity with determined risk factors, which generally has a negative impact on quality of life. Obstructive sleep-disordered breathing (SDB), often referred to as obstructive sleep apnea, stands among the possible risk factors for ED. DISCUSSION: Literature review suggests that SDB induces a spectrum of abnormalities in neural, hormonal, and vascular regulation that may contribute to the development of ED. While more studies are required to imply SDB as a risk factor for ED, several case series and expert opinion have contributed evidence for a causal relationship.
CONCLUSION: In clinical practice, men presenting with symptoms of sexual dysfunction often have concomitant sleep disorders requiring treatment. There is now evidence to suggest that treating SDB may be an effective treatment for ED. It is the authors' opinion that patients with erectile dysfunction would benefit from a sleep evaluation.

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Year:  2008        PMID: 18766395     DOI: 10.1007/s11325-008-0212-8

Source DB:  PubMed          Journal:  Sleep Breath        ISSN: 1520-9512            Impact factor:   2.816


  83 in total

1.  Erectile dysfunction in sleep apnea and response to CPAP.

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2.  A double-blind, placebo-controlled, crossover study of sildenafil in obstructive sleep apnea.

Authors:  Suely Roizenblatt; Christian Guilleminault; Dalva Poyares; Fátima Cintra; Adriana Kauati; Sergio Tufik
Journal:  Arch Intern Med       Date:  2006-09-18

3.  Cigarette smoking: an independent risk factor for atherosclerosis in the hypogastric-cavernous arterial bed of men with arteriogenic impotence.

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Journal:  J Urol       Date:  1991-04       Impact factor: 7.450

4.  Erectile dysfunction, obstructive sleep apnea syndrome and nasal CPAP treatment.

Authors:  M A Gonçalves; C Guilleminault; E Ramos; A Palha; T Paiva
Journal:  Sleep Med       Date:  2005-07       Impact factor: 3.492

Review 5.  Obstructive sleep apnea: an update on mechanisms and cardiovascular consequences.

Authors:  Jacek Wolf; Joanna Lewicka; Krzysztof Narkiewicz
Journal:  Nutr Metab Cardiovasc Dis       Date:  2007-02-20       Impact factor: 4.222

6.  Erectile dysfunction in type 1 and type 2 diabetics in Italy. On behalf of Gruppo Italiano Studio Deficit Erettile nei Diabetici.

Authors:  D Fedele; A Bortolotti; C Coscelli; F Santeusanio; L Chatenoud; E Colli; M Lavezzari; M Landoni; F Parazzini
Journal:  Int J Epidemiol       Date:  2000-06       Impact factor: 7.196

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Authors:  H S Schmidt; H A Wise
Journal:  J Urol       Date:  1981-09       Impact factor: 7.450

8.  Increased incidence of depressive symptoms in men with erectile dysfunction.

Authors:  R Shabsigh; L T Klein; S Seidman; S A Kaplan; B J Lehrhoff; J S Ritter
Journal:  Urology       Date:  1998-11       Impact factor: 2.649

9.  Serum testosterone depression associated with hypoxia in respiratory failure.

Authors:  P D Semple; G H Beastall; W S Watson; R Hume
Journal:  Clin Sci (Lond)       Date:  1980-01       Impact factor: 6.124

10.  Effect of testosterone on the apneic threshold in women during NREM sleep.

Authors:  X S Zhou; J A Rowley; F Demirovic; M P Diamond; M S Badr
Journal:  J Appl Physiol (1985)       Date:  2002-09-13
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  9 in total

1.  Integrating sleep management into clinical practice.

Authors:  Catherine C Schuman; Hrayr P Attarian
Journal:  J Clin Psychol Med Settings       Date:  2012-03

2.  Sexual functioning of men and women with severe obesity before bariatric surgery.

Authors:  Kristine J Steffen; Wendy C King; Gretchen E White; Leslee L Subak; James E Mitchell; Anita P Courcoulas; David R Flum; Gladys Strain; David B Sarwer; Ronette L Kolotkin; Walter Pories; Alison J Huang
Journal:  Surg Obes Relat Dis       Date:  2016-09-28       Impact factor: 4.734

3.  Obstructive sleep apnea symptoms beyond sleepiness and snoring: effects of nasal APAP therapy.

Authors:  Ivo A C Cruz; Marta Drummond; João C Winck
Journal:  Sleep Breath       Date:  2011-03-02       Impact factor: 2.816

Review 4.  Erectile Dysfunction and Obstructive Sleep Apnea: A Review.

Authors:  Yiwei Gu; ChangJing Wu; Feng Qin; Jiuhong Yuan
Journal:  Front Psychiatry       Date:  2022-05-26       Impact factor: 5.435

5.  Prospective study of restless legs syndrome and risk of erectile dysfunction.

Authors:  Yanping Li; Salma Batool-Anwar; Sehee Kim; Eric B Rimm; Alberto Ascherio; Xiang Gao
Journal:  Am J Epidemiol       Date:  2013-04-21       Impact factor: 4.897

Review 6.  Sleeping Beauty or the Beast? - Metabolic Syndrome from an Obstructive Sleep Apnoea Perspective.

Authors:  Lise Tarnow; Brigitte Klinkenbijl; Holger Woehrle
Journal:  Eur Endocrinol       Date:  2013-03-15

7.  Erectile Dysfunction in Patients with Sleep Apnea--A Nationwide Population-Based Study.

Authors:  Chia-Min Chen; Ming-Ju Tsai; Po-Ju Wei; Yu-Chung Su; Chih-Jen Yang; Meng-Ni Wu; Chung-Yao Hsu; Shang-Jyh Hwang; Inn-Wen Chong; Ming-Shyan Huang
Journal:  PLoS One       Date:  2015-07-15       Impact factor: 3.240

8.  Prevalence and Characteristics of Erectile Dysfunction in Obstructive Sleep Apnea Patients.

Authors:  Chen Feng; Yan Yang; Lixiao Chen; Ruixiang Guo; Huayang Liu; Chaojie Li; Yan Wang; Pin Dong; Yanzhong Li
Journal:  Front Endocrinol (Lausanne)       Date:  2022-02-18       Impact factor: 5.555

9.  Erectile dysfunction in obstructive sleep apnea patients: A randomized trial on the effects of Continuous Positive Airway Pressure (CPAP).

Authors:  Mercè Pascual; Jordi de Batlle; Ferran Barbé; Anabel L Castro-Grattoni; Josep M Auguet; Lydia Pascual; Manel Vilà; Anunciación Cortijo; Manuel Sánchez-de-la-Torre
Journal:  PLoS One       Date:  2018-08-08       Impact factor: 3.240

  9 in total

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