Literature DB >> 18765936

Fetal cardiac diagnosis and its influence on the pregnancy and newborn--a tertiary centre experience.

B K Yeu1, R Chalmers, P Shekleton, J Grimwade, S Menahem.   

Abstract

OBJECTIVES: To evaluate the impact of an abnormal fetal cardiac scan on the management of the pregnancy and the outcome of the newborn.
METHODS: We reviewed all pregnancies that were referred to the Fetal Cardiac Unit for assessment to determine if the finding of a cardiac abnormality influenced the pregnancy and fetus, timing and mode of delivery, the treatment and outcome of the newborn. Diagnoses were confirmed by echocardiography following the baby's delivery.
RESULTS: Between January 2005 and July 2006, there were 251 detailed fetal cardiac scans carried out on at risk pregnancies or those with suspected abnormal scans in 127 fetuses. Seven of the 92 mothers with abnormal fetal cardiac scans opted for termination. Two were successfully treated during the pregnancy for hydrops fetalis arising from a tachyarrhythmia. One was induced early because of deterioration of fetal well-being and increasing cardiac size. Twenty-six infants required a prostaglandin infusion prior to surgery. Two required intensive care for associated malformations. There were 24 survivors following complex surgery, and 2 deaths. Two infants with severe tricuspid valve incompetence from a dysplastic valve died, one associated with a septicaemia and the other where surgery was delayed because of prematurity and low birth weight. There was no maternal morbidity or mortality.
CONCLUSIONS: Early detection of fetal cardiac malformation allows for careful counselling of the parents, ongoing antenatal review with a planned site and timing of delivery, and anticipatory postnatal care for optimum outcomes. The importance of careful screening is emphasized to allow for referral of mothers with potentially abnormal scans to an appropriate tertiary centre for confirmation and management. Copyright 2008 S. Karger AG, Basel.

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Mesh:

Year:  2008        PMID: 18765936     DOI: 10.1159/000151669

Source DB:  PubMed          Journal:  Fetal Diagn Ther        ISSN: 1015-3837            Impact factor:   2.587


  5 in total

Review 1.  Efficacy of prenatal diagnosis of major congenital heart disease on perinatal management and perioperative mortality: a meta-analysis.

Authors:  Yi-Fei Li; Kai-Yu Zhou; Jie Fang; Chuan Wang; Yi-Min Hua; De-Zhi Mu
Journal:  World J Pediatr       Date:  2016-04-08       Impact factor: 2.764

2.  Mode of delivery in pregnancies complicated by major fetal congenital heart disease: a retrospective cohort study.

Authors:  C A Walsh; A MacTiernan; S Farrell; C Mulcahy; C J McMahon; O Franklin; D Coleman; R Mahony; S Higgins; S Carroll; P McParland; F M McAuliffe
Journal:  J Perinatol       Date:  2014-05-29       Impact factor: 2.521

Review 3.  "Functionally" univentricular hearts: impact of pre-natal diagnosis.

Authors:  Antonio Francesco Corno
Journal:  Front Pediatr       Date:  2015-02-27       Impact factor: 3.418

4.  Performance of different scan protocols of fetal echocardiography in the diagnosis of fetal congenital heart disease: a systematic review and meta-analysis.

Authors:  Yifei Li; Yimin Hua; Jie Fang; Chuan Wang; Lina Qiao; Chaomin Wan; Dezhi Mu; Kaiyu Zhou
Journal:  PLoS One       Date:  2013-06-04       Impact factor: 3.240

5.  Feasibility Study on Prenatal Cardiac Screening Using Four-Dimensional Ultrasound with Spatiotemporal Image Correlation: A Multicenter Study.

Authors:  Liqing Zhao; Yurong Wu; Sun Chen; Yunyun Ren; Ping Chen; Jianmei Niu; Cao Li; Kun Sun
Journal:  PLoS One       Date:  2016-06-17       Impact factor: 3.240

  5 in total

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