OBJECTIVE: A growing number of studies have tested the efficacy of preventive interventions in reducing the incidence of depressive disorders. Until now, no meta-analysis has integrated the results of these studies. METHOD: The authors conducted a meta-analysis. After a comprehensive literature search, 19 studies were identified that met inclusion criteria. The studies had to be randomized controlled studies in which the incidence of depressive disorders (based on diagnostic criteria) in an experimental group could be compared with that of a control group. RESULTS: The mean incidence rate ratio was 0.78, indicating a reduction of the incidence of depressive disorders by 22% in experimental compared with control groups. Heterogeneity was low to moderate (I(2)=33%). The number needed to treat to prevent one case of depressive disorder was 22. Moderator analyses revealed no systematic differences between target populations or types of prevention (universal, selective, or indicated). The data included indications that prevention based on interpersonal psychotherapy may be more effective than prevention based on cognitive-behavioral therapy. CONCLUSIONS: Prevention of new cases of depressive disorders does seem to be possible. Prevention may become an important way, in addition to treatment, to reduce the enormous public health burden of depression in the coming years.
OBJECTIVE: A growing number of studies have tested the efficacy of preventive interventions in reducing the incidence of depressive disorders. Until now, no meta-analysis has integrated the results of these studies. METHOD: The authors conducted a meta-analysis. After a comprehensive literature search, 19 studies were identified that met inclusion criteria. The studies had to be randomized controlled studies in which the incidence of depressive disorders (based on diagnostic criteria) in an experimental group could be compared with that of a control group. RESULTS: The mean incidence rate ratio was 0.78, indicating a reduction of the incidence of depressive disorders by 22% in experimental compared with control groups. Heterogeneity was low to moderate (I(2)=33%). The number needed to treat to prevent one case of depressive disorder was 22. Moderator analyses revealed no systematic differences between target populations or types of prevention (universal, selective, or indicated). The data included indications that prevention based on interpersonal psychotherapy may be more effective than prevention based on cognitive-behavioral therapy. CONCLUSIONS: Prevention of new cases of depressive disorders does seem to be possible. Prevention may become an important way, in addition to treatment, to reduce the enormous public health burden of depression in the coming years.
Authors: Emily Feinberg; Rachel Stein; Yaminette Diaz-Linhart; Lucia Egbert; William Beardslee; Mark T Hegel; Michael Silverstein Journal: Fam Community Health Date: 2012 Jan-Mar
Authors: Su-Chin Serene Olin; Mary McCord; Ruth E K Stein; Bonnie D Kerker; Dara Weiss; Kimberly E Hoagwood; Sarah M Horwitz Journal: J Womens Health (Larchmt) Date: 2017-04-14 Impact factor: 2.681
Authors: Kim van Zoonen; Claudia Buntrock; David Daniel Ebert; Filip Smit; Charles F Reynolds; Aartjan T F Beekman; Pim Cuijpers Journal: Int J Epidemiol Date: 2014-04 Impact factor: 7.196
Authors: Karlijn J Joling; Filip Smit; Harm W J van Marwijk; Henriëtte E van der Horst; Philip Scheltens; Richard Schulz; Hein P J van Hout Journal: Int Psychogeriatr Date: 2011-09-01 Impact factor: 3.878
Authors: Bruce E Compas; Rex Forehand; Gary Keller; Jennifer E Champion; Aaron Rakow; Kristen L Reeslund; Laura McKee; Jessica M Fear; Christina J M Colletti; Emily Hardcastle; Mary Jane Merchant; Lori Roberts; Jennifer Potts; Emily Garai; Nicole Coffelt; Erin Roland; Sonya K Sterba; David A Cole Journal: J Consult Clin Psychol Date: 2009-12
Authors: Caroline Kuo; Ashleigh LoVette; Dan J Stein; Lucie D Cluver; Larry K Brown; Millicent Atujuna; Tracy R G Gladstone; Jacqueline Martin; William Beardslee Journal: Transcult Psychiatry Date: 2018-10-05