Literature DB >> 18765289

Inteferons pen the JAK-STAT pathway.

Christian Schindler1, Courtney Plumlee.   

Abstract

Characterization of how interferons (IFNs) mediate their biological response led to identification of the JAK-STAT signaling cascade, where JAKs are receptor-associated kinases and STATs the transcription factors they activate. Today, 4 JAKs and 7 STATs are known to transduce pivotal signals for the over 50 members of the four-helix bundle family of cytokines. This review will provide an overview and historical perspective of the JAK-STAT paradigm.

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Year:  2008        PMID： 18765289      PMCID： PMC2741134          DOI： 10.1016/j.semcdb.2008.08.010

Source DB:  PubMed          Journal:  Semin Cell Dev Biol        ISSN： 1084-9521            Impact factor:   7.727


  155 in total

1.  Stat3 and Stat4: members of the family of signal transducers and activators of transcription.

Authors:  Z Zhong; Z Wen; J E Darnell
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-24       Impact factor: 11.205

2.  Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes.

Authors:  M Kawamura; D W McVicar; J A Johnston; T B Blake; Y Q Chen; B K Lal; A R Lloyd; D J Kelvin; J E Staples; J R Ortaldo
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-05       Impact factor: 11.205

3.  Transcription factor ISGF-3 formation requires phosphorylated Stat91 protein, but Stat113 protein is phosphorylated independently of Stat91 protein.

Authors:  T Improta; C Schindler; C M Horvath; I M Kerr; G R Stark; J E Darnell
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-24       Impact factor: 11.205

4.  An interleukin-4-induced transcription factor: IL-4 Stat.

Authors:  J Hou; U Schindler; W J Henzel; T C Ho; M Brasseur; S L McKnight
Journal:  Science       Date:  1994-09-16       Impact factor: 47.728

5.  Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway.

Authors:  S Akira; Y Nishio; M Inoue; X J Wang; S Wei; T Matsusaka; K Yoshida; T Sudo; M Naruto; T Kishimoto
Journal:  Cell       Date:  1994-04-08       Impact factor: 41.582

6.  Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals.

Authors:  U Klingmüller; U Lorenz; L C Cantley; B G Neel; H F Lodish
Journal:  Cell       Date:  1995-03-10       Impact factor: 41.582

7.  Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation.

Authors:  K Yamamoto; F W Quelle; W E Thierfelder; B L Kreider; D J Gilbert; N A Jenkins; N G Copeland; O Silvennoinen; J N Ihle
Journal:  Mol Cell Biol       Date:  1994-07       Impact factor: 4.272

8.  Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.

Authors:  H Wakao; F Gouilleux; B Groner
Journal:  EMBO J       Date:  1994-05-01       Impact factor: 11.598

9.  Interleukin-3 signals through multiple isoforms of Stat5.

Authors:  M Azam; H Erdjument-Bromage; B L Kreider; M Xia; F Quelle; R Basu; C Saris; P Tempst; J N Ihle; C Schindler
Journal:  EMBO J       Date:  1995-04-03       Impact factor: 11.598

10.  Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

Authors:  A L Mui; H Wakao; A M O'Farrell; N Harada; A Miyajima
Journal:  EMBO J       Date:  1995-03-15       Impact factor: 11.598
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  94 in total

Review 1.  Mast cell homeostasis and the JAK-STAT pathway.

Authors:  J K Morales; Y T Falanga; A Depcrynski; J Fernando; J J Ryan
Journal:  Genes Immun       Date:  2010-06-10       Impact factor: 2.676

2.  Dietary compounds as potent inhibitors of the signal transducers and activators of transcription (STAT) 3 regulatory network.

Authors:  Anne Trécul; Franck Morceau; Mario Dicato; Marc Diederich
Journal:  Genes Nutr       Date:  2012-01-25       Impact factor: 5.523

Review 3.  The Jak/STAT pathway.

Authors:  Douglas A Harrison
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-03-01       Impact factor: 10.005

4.  Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling.

Authors:  Byung Hak Kim; Yun Sook Min; Jung Sook Choi; Gyeong Hun Baeg; Young Soo Kim; Jong Wook Shin; Tae Yoon Kim; Sang Kyu Ye
Journal:  Exp Mol Med       Date:  2011-05-31       Impact factor: 8.718

5.  Interferons direct an effective innate response to Legionella pneumophila infection.

Authors:  Courtney R Plumlee; Carolyn Lee; Amer A Beg; Thomas Decker; Howard A Shuman; Christian Schindler
Journal:  J Biol Chem       Date:  2009-08-31       Impact factor: 5.157

6.  Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures.

Authors:  Svetlana Marukian; Linda Andrus; Timothy P Sheahan; Christopher T Jones; Edgar D Charles; Alexander Ploss; Charles M Rice; Lynn B Dustin
Journal:  Hepatology       Date:  2011-12       Impact factor: 17.425

7.  Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.

Authors:  William R Lagor; David W Fields; Robert C Bauer; Alison Crawford; Michael C Abt; David Artis; E John Wherry; Daniel J Rader
Journal:  Atherosclerosis       Date:  2014-01-10       Impact factor: 5.162

8.  Interferon alpha induced intrahepatic pSTAT1 inversely correlate with serum HCV RNA levels in chronic HCV infection.

Authors:  Feyza Gunduz; Chaithanya Mallikarjun; Luis A Balart; Srikanta Dash
Journal:  Exp Mol Pathol       Date:  2013-11-08       Impact factor: 3.362

9.  NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3.

Authors:  Byung-Hak Kim; Jun-Goo Jee; Chang-Hong Yin; Claudio Sandoval; Somasundaram Jayabose; Daisuke Kitamura; Erika A Bach; Gyeong-Hun Baeg
Journal:  Mol Cancer       Date:  2010-02-11       Impact factor: 27.401

10.  Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology.

Authors:  Hideaki Tahara; Marimo Sato; Magdalena Thurin; Ena Wang; Lisa H Butterfield; Mary L Disis; Bernard A Fox; Peter P Lee; Samir N Khleif; Jon M Wigginton; Stefan Ambs; Yasunori Akutsu; Damien Chaussabel; Yuichiro Doki; Oleg Eremin; Wolf Hervé Fridman; Yoshihiko Hirohashi; Kohzoh Imai; James Jacobson; Masahisa Jinushi; Akira Kanamoto; Mohammed Kashani-Sabet; Kazunori Kato; Yutaka Kawakami; John M Kirkwood; Thomas O Kleen; Paul V Lehmann; Lance Liotta; Michael T Lotze; Michele Maio; Anatoli Malyguine; Giuseppe Masucci; Hisahiro Matsubara; Shawmarie Mayrand-Chung; Kiminori Nakamura; Hiroyoshi Nishikawa; A Karolina Palucka; Emanuel F Petricoin; Zoltan Pos; Antoni Ribas; Licia Rivoltini; Noriyuki Sato; Hiroshi Shiku; Craig L Slingluff; Howard Streicher; David F Stroncek; Hiroya Takeuchi; Minoru Toyota; Hisashi Wada; Xifeng Wu; Julia Wulfkuhle; Tomonori Yaguchi; Benjamin Zeskind; Yingdong Zhao; Mai-Britt Zocca; Francesco M Marincola
Journal:  J Transl Med       Date:  2009-06-17       Impact factor: 5.531
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