| Literature DB >> 187631 |
L M Golub, K Siegel, N S Ramamurthy, I D Mandel.
Abstract
Collagenase activity in human gingival fluid was measured using a radioactive collagen fibril assay. The activity was positively correlated with the severity of gingival disease. The fluid collagenase seemed to be controlled by alpha 2-macroglobulin, based on its activation by NaSCN, and to be present solely in the extracellular fraction. Examination of the collagen breakdown products by acrylamide gel electrophoresis indicated that the fluid collagenase was of tissue rather than bacterial origin.Entities:
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Year: 1976 PMID： 187631 DOI： 10.1177/00220345760550060701
Source DB: PubMed Journal: J Dent Res ISSN： 0022-0345 Impact factor: 6.116