Literature DB >> 18762979

Prospective study on antibiotics misuse among infants with upper respiratory infections.

Manal F El Sayed1, Hala Tamim, Diana Jamal, Ghina Mumtaz, Imad Melki, Khalid Yunis.   

Abstract

BACKGROUND: The judicious prescription of antibiotics has become a central focus of professional and public health measures to combat the spread of resistant organisms.
MATERIALS AND METHODS: A one-year multi-center prospective follow-up study of 1,320 healthy infants was conducted. The study aim was to determine the prevalence and identify the predictors of antibiotics misuse in viral respiratory illnesses among healthy infants in the first year of life. Infants born between August 2001 and February 2002 were recruited through the clinics and dispensaries of 117 pediatricians located in the Greater Beirut area of Lebanon. On each routine visit from birth until one year of life, pediatricians reported any episodes of upper respiratory tract infection (URTI; common cold) and bronchiolitis, as well as the treatment type, duration, and dose. Predictors that were considered included infant, maternal, and pediatrician characteristics.
RESULTS: Of the 1,320 recruited infants, 770 (58.3%) had common cold or acute bronchiolitis on at least one occasion during the study period. Pediatricians prescribed antibiotics at least once in 21.4% of cases diagnosed as the common cold and 45.5% of cases of acute bronchiolitis. Logistic regression analysis revealed that antibiotics misuse was more common among infants born to mothers with lower educational levels (odds ratio [OR] = 1.6; 95% confidence interval [CI]: 1.1-2.3). Furthermore, pediatricians tend to prescribe antibiotics in dispensaries more often than in private clinics (OR = 1.4; 95% CI: 1.0-2.3).
CONCLUSION: This study shows a substantial quantity of antibiotics prescriptions for common cold and acute bronchiolitis in our population. Our findings suggest that lower maternal education and pediatricians working in dispensaries (versus private clinics) are associated with increased antibiotics misuse.

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Year:  2008        PMID: 18762979     DOI: 10.1007/s00431-008-0815-x

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  40 in total

1.  Impact of a waiting room videotape message on parent attitudes toward pediatric antibiotic use.

Authors:  J G Wheeler; M Fair; P M Simpson; L A Rowlands; M E Aitken; R F Jacobs
Journal:  Pediatrics       Date:  2001-09       Impact factor: 7.124

2.  Antibiotic use in the first year of life and asthma in early childhood.

Authors:  J C Celedón; A Fuhlbrigge; S Rifas-Shiman; S T Weiss; J A Finkelstein
Journal:  Clin Exp Allergy       Date:  2004-07       Impact factor: 5.018

3.  Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physicians.

Authors:  R Gonzales; J F Steiner; M A Sande
Journal:  JAMA       Date:  1997-09-17       Impact factor: 56.272

4.  General practitioners' patterns of antimicrobial drugs prescription in the therapy of acute pharyngitis.

Authors:  M Katić; V Katić; D Ivanković; J Culig; A Budak
Journal:  Scand J Prim Health Care       Date:  2000-03       Impact factor: 2.581

5.  [Epidemiology and antimicrobial resistance of Streptococcus pneumoniae strains isolated in Ile de France area during 2001].

Authors:  M C Demachy; F Faibis; A Artigou; C Benoit; E Cambau; A Cecille; E Chachaty; C Chaplain; P Cormier; F Cousinard; J C Decotte; D Demontrond; A Dublanchet; C Dupeyron; A Farges; B Ferre; A P Fremaux; M J Galanti; C Gallet; P Guiet; B Hacquard; M Hornstein; P Legrand; F Le Manach; N Lucet; C Malbrunot; A Mangeol; D Mathieu; G Otterbein; F Pateyron; I Poilane; J Pollet; T Rabenja; C Spicq
Journal:  Med Mal Infect       Date:  2004-07       Impact factor: 2.152

Review 6.  Judicious use of antibiotics for common pediatric respiratory infections.

Authors:  R F Jacobs
Journal:  Pediatr Infect Dis J       Date:  2000-09       Impact factor: 2.129

7.  Socio-economic differences in daycare arrangements and use of medical care and antibiotics in Swedish preschool children.

Authors:  A Hjern; B Haglund; F Rasmussen; M Rosén
Journal:  Acta Paediatr       Date:  2000-10       Impact factor: 2.299

8.  Effectiveness of a multiple intervention to reduce antibiotic prescribing for respiratory tract symptoms in primary care: randomised controlled trial.

Authors:  Ineke Welschen; Marijke M Kuyvenhoven; Arno W Hoes; Theo J M Verheij
Journal:  BMJ       Date:  2004-08-05

9.  Drug consumption during the first 18 months of life of infants from smoking and non-smoking families.

Authors:  A Håkansson; C Petersson
Journal:  Br J Gen Pract       Date:  1992-09       Impact factor: 5.386

10.  Misconceptions about colds and predictors of health service utilization.

Authors:  Grace M Lee; Jennifer F Friedman; Dennis Ross-Degnan; Patricia L Hibberd; Donald A Goldmann
Journal:  Pediatrics       Date:  2003-02       Impact factor: 7.124

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1.  Bronchiolitis in children: The Saudi initiative of bronchiolitis diagnosis, management, and prevention (SIBRO).

Authors:  Adel S Alharbi; Mansour Alqwaiee; Mohammed Y Al-Hindi; Rafat Mosalli; Abdullah Al-Shamrani; Saleh Alharbi; Abdullah Yousef; Amal Al Aidaroos; Turki Alahmadi; Aisha Alshammary; Abeer Miqdad; Yazan Said; Abdulrahman Alnemri
Journal:  Ann Thorac Med       Date:  2018 Jul-Sep       Impact factor: 2.219

2.  Antibiotic prescriptions in acute otitis media and pharyngitis in Italian pediatric outpatients.

Authors:  E Barbieri; D Donà; A Cantarutti; R Lundin; A Scamarcia; G Corrao; L Cantarutti; C Giaquinto
Journal:  Ital J Pediatr       Date:  2019-08-17       Impact factor: 2.638

3.  Viral aetiology of common colds of outpatient children at primary care level and the use of antibiotics.

Authors:  Janete Kamikawa; Celso Francisco Hernandes Granato; Nancy Bellei
Journal:  Mem Inst Oswaldo Cruz       Date:  2015-11       Impact factor: 2.743

  3 in total

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