| Literature DB >> 18762351 |
Toshio Sugane1, Masayuki Baba, Reiko Imai, Mio Nakajima, Naoyoshi Yamamoto, Tadaaki Miyamoto, Hidefumi Ezawa, Kyousan Yoshikawa, Susumu Kandatsu, Tadashi Kamada, Junetsu Mizoe, Hirohiko Tsujii.
Abstract
Surgical resection is the standard treatment for stage I non-small cell lung cancer (NSCLC). However, elderly patients with NSCLC often suffer from other conditions, such as chronic obstructive pulmonary disease (COPD) or cardiovascular disease, and are not suitable candidates for surgery. Different modalities to treat stage I NSCLC have been developed, such as stereotactic radiotherapy (SRT), proton beam radiotherapy and carbon ion radiotherapy (CIRT). Between April 1999 and November 2003, we treated 129 patients with stage I NSCLC using CIRT. In this study, we focused on 28 patients aged 80 years and older who underwent CIRT, and analyzed the effectiveness of CIRT in treating their lung cancer and the impact on their activity of daily life (ADL). The 5-year local control rate for these patients was 95.8%, and the 5-year overall survival rate was 30.7%, but there were no patients who started home oxygen therapy or had decreased ADL. Our data demonstrate that CIRT was effective in treating elderly patients with stage I NSCLC.Entities:
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Year: 2008 PMID： 18762351 DOI： 10.1016/j.lungcan.2008.07.007
Source DB: PubMed Journal: Lung Cancer ISSN： 0169-5002 Impact factor: 5.705