Literature DB >> 18762174

Cathepsin D: a cellular roadmap.

Nousheen Zaidi1, Andreas Maurer, Sebastian Nieke, Hubert Kalbacher.   

Abstract

Cathepsin D is a normal and major component of lysosomes, it is found in almost all cells and tissues of mammals. Present review describes different events in cellular life of cathepsin D mainly its biosynthesis, co-translational and posttranslational modifications, targeting to lysosomes and proteolytic processing and maturation within lysosomes.

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Year:  2008        PMID： 18762174     DOI： 10.1016/j.bbrc.2008.08.099

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  80 in total

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