Literature DB >> 18761755

A cluster randomized controlled trial of cognitive behaviour therapy for common mental disorders in patients with advanced cancer.

S Moorey1, E Cort, M Kapari, B Monroe, P Hansford, K Mannix, M Henderson, L Fisher, M Hotopf.   

Abstract

BACKGROUND: Cognitive behaviour therapy (CBT) has been shown to reduce psychological morbidity in people with cancer, but no randomized controlled trial (RCT) exists in palliative care. We aimed to determine whether home care nurses could be taught to deliver basic cognitive behavioural techniques and so reduce symptoms of anxiety and depression.
METHOD: Clinical nurse specialists (CNSs) at St Christopher's Hospice were randomly allocated to receive training in CBT or continue their usual practice. At the end of the trial, nurses were rated on the Cognitive Therapy First Aid Rating Scale (CTFARS) for CBT competence. Home care patients who scored as possible cases on the Hospital Anxiety and Depression Scale (HADS) entered the trial. Participants received home care nursing visits. Assessments were carried out at baseline, 6, 10 and 16 weeks.
RESULTS: Eight nurses received CBT training and seven continued practice as usual. The mean CTFARS scores were 35.9 for the CBT nurses and 19.0 for the controls (p=0.02). A total of 328 patients (54%) were possible cases and 80 entered the trial; most of those excluded were too ill to participate. There was an interaction between group and time: individuals receiving CBT had lower anxiety scores over time [coefficient -0.20, 95% confidence interval (CI) -0.35 to -0.05, p=0.01]. No effect of the training was found for depression.
CONCLUSIONS: It is possible to conduct a randomized trial of psychological interventions in palliative care but there is considerable attrition from physical morbidity and mortality. Nurses can learn to integrate basic CBT methods into their clinical practice. This training may be associated with better outcomes for symptoms of anxiety.

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Year:  2008        PMID: 18761755     DOI: 10.1017/S0033291708004169

Source DB:  PubMed          Journal:  Psychol Med        ISSN: 0033-2917            Impact factor:   7.723


  20 in total

1.  Factors associated with attrition from a randomized controlled trial of meaning-centered group psychotherapy for patients with advanced cancer.

Authors:  Allison J Applebaum; Wendy G Lichtenthal; Hayley A Pessin; Julia N Radomski; N Simay Gökbayrak; Aviva M Katz; Barry Rosenfeld; William Breitbart
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2.  Expert opinion on detecting and treating depression in palliative care: A Delphi study.

Authors:  Lauren Rayner; Annabel Price; Matthew Hotopf; Irene J Higginson
Journal:  BMC Palliat Care       Date:  2011-05-27       Impact factor: 3.234

3.  The Epidemiology of Depressive Symptoms in the Last Year of Life.

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4.  [Psychiatric comorbidities in visceral surgery patients with cancer].

Authors:  O Krauss; J Hauss; S Jonas; S Leinung; U Halm; C Albani; S Singer
Journal:  Chirurg       Date:  2011-03       Impact factor: 0.955

Review 5.  Drug therapy for symptoms associated with anxiety in adult palliative care patients.

Authors:  Susan Salt; Caroline A Mulvaney; Nancy J Preston
Journal:  Cochrane Database Syst Rev       Date:  2017-05-18

6.  A pilot randomized controlled trial of brief cognitive-behavioral therapy for anxiety in patients with terminal cancer.

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Journal:  Oncologist       Date:  2012-06-11

Review 7.  Populations and Interventions for Palliative and End-of-Life Care: A Systematic Review.

Authors:  Adam E Singer; Joy R Goebel; Yan S Kim; Sydney M Dy; Sangeeta C Ahluwalia; Megan Clifford; Elizabeth Dzeng; Claire E O'Hanlon; Aneesa Motala; Anne M Walling; Jaime Goldberg; Daniella Meeker; Claudia Ochotorena; Roberta Shanman; Mike Cui; Karl A Lorenz
Journal:  J Palliat Med       Date:  2016-08-17       Impact factor: 2.947

Review 8.  Clinical considerations for working with patients with advanced cancer.

Authors:  Megan Taylor-Ford
Journal:  J Clin Psychol Med Settings       Date:  2014-09

Review 9.  Effects of screening for psychological distress on patient outcomes in cancer: a systematic review.

Authors:  Anna Meijer; Michelle Roseman; Vanessa C Delisle; Katherine Milette; Brooke Levis; Achyuth Syamchandra; Michael E Stefanek; Donna E Stewart; Peter de Jonge; James C Coyne; Brett D Thombs
Journal:  J Psychosom Res       Date:  2013-02-27       Impact factor: 3.006

Review 10.  A systematic review of cognitive behavioral interventions in advanced cancer.

Authors:  Cathy L Campbell; Lisa C Campbell
Journal:  Patient Educ Couns       Date:  2012-07-12
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