| Literature DB >> 18761342 |
Milena Svobodová1, Bulent Alten, Lenka Zídková, Vít Dvorák, Jitka Hlavacková, Jitka Mysková, Veronika Seblová, Ozge Erisoz Kasap, Asli Belen, Jan Votýpka, Petr Volf.
Abstract
Transmission of cutaneous leishmaniasis (CL) caused by Leishmania infantum was studied in South Anatolia, Turkey. Small, non-ulcerating lesions prevailed and patients were negative in rK39 tests for antibody detection for human visceral leishmaniasis (VL). The most abundant sand fly species, Phlebotomus tobbi, was found positive for Leishmania promastigotes with a prevalence of 1.4% (13 out of 898 dissected females). The isolated strains were identical with those obtained from patients with CL and were typed as L. infantum. Phylogenetic analysis revealed similarity to MON-188 and a clear difference from the MON-1 clade. Blood-meal identification showed that P. tobbi feeds preferentially on cattle and humans. This finding, the high number of CL patients and relative scarcity of dogs in the focus, suggests that the transmission cycle could be anthroponotic.Entities:
Mesh：
Year: 2008 PMID： 18761342 DOI： 10.1016/j.ijpara.2008.06.016
Source DB: PubMed Journal: Int J Parasitol ISSN： 0020-7519 Impact factor: 3.981