| Literature DB >> 18760647 |
Michael R Lappin1, Edward Breitschwerdt, Melissa Brewer, Jennifer Hawley, Barbara Hegarty, Steven Radecki.
Abstract
The purpose of this study was to determine whether there are associations between Bartonella species antibody (enzyme-linked immunosorbent assay (ELISA) and Western blot (WB)) and polymerase chain reaction assay results in cats with and without fever. Afebrile control cats (39/93; 42.0%) were more likely to have Bartonella species antibodies than cats with fever (29/93; 31.2%). The difference in prevalence of Bartonella species deoxyribonucleic acid (DNA) in blood of cats with fever (14/81; 17.3%) as compared to afebrile control cats (6/81; 7.4%) approached statistical significance (P=0.0571). Bartonella species ELISA or WB results frequently did not correlate to the presence or absence of Bartonella species DNA in blood. The results of this study indicate that in cats, Bartonella species antibody tests cannot predict whether fever is due to Bartonella species infection and should not be used to determine the Bartonella species infection status.Entities:
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Year: 2008 PMID： 18760647 DOI： 10.1016/j.jfms.2008.06.005
Source DB: PubMed Journal: J Feline Med Surg ISSN： 1098-612X Impact factor: 2.015