Literature DB >> 18759482

Synthesis of cribrostatin 6.

Michael D Markey1, T Ross Kelly.   

Abstract

The synthesis of cribrostatin 6 (1) is described. A regioselective bromination, a biaryl coupling, and an intramolecular cyclization are the key steps in the synthesis.

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Year:  2008        PMID： 18759482     DOI： 10.1021/jo801694w

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  Tandem Electrocyclic Ring Opening/Radical Cyclization: Application to the Total Synthesis of Cribrostatin 6.

Authors:  Daniel Knueppel; Stephen F Martin
Journal:  Tetrahedron       Date:  2011-12-23       Impact factor: 2.457

Review 2.  Antibacterials from the sea.

Authors:  Chambers C Hughes; William Fenical
Journal:  Chemistry       Date:  2010-11-08       Impact factor: 5.236

3.  Total synthesis of cribrostatin 6.

Authors:  Daniel Knueppel; Stephen F Martin
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

4.  Cribrostatin 6 induces death in cancer cells through a reactive oxygen species (ROS)-mediated mechanism.

Authors:  Mirth T Hoyt; Rahul Palchaudhuri; Paul J Hergenrother
Journal:  Invest New Drugs       Date:  2010-02-20       Impact factor: 3.850

5.  Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5- a]pyridines.

Authors:  Santosh Kurhade; Elmar Diekstra; Fandi Sutanto; Katarzyna Kurpiewska; Justyna Kalinowska-Tłuścik; Alexander Dömling
Journal:  Org Lett       Date:  2018-06-26       Impact factor: 6.005

6.  The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions.

Authors:  Zicong Yan; Changfeng Wan; Yu Yang; Zhenggen Zha; Zhiyong Wang
Journal:  RSC Adv       Date:  2018-06-25       Impact factor: 3.361
  6 in total

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