Literature DB >> 18758631

Target-driven selection in a dynamic nitrone library.

Simon M Turega1, Christiane Lorenz, Jan W Sadownik, Douglas Philp.   

Abstract

Nitrones undergo dynamic exchange in chloroform at room temperature through two mechanisms-hydrolysis and recombination or hydroxylamine addition/elimination; this dynamic exchange is harnessed to select a nitrone-based bis(amidopyridine) receptor for diacids from a group of four nitrones through its binding to a glutaric acid-based target.

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Year:  2008        PMID: 18758631     DOI: 10.1039/b805945d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  4 in total

1.  Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry.

Authors:  Venugopal T Bhat; Anne M Caniard; Torsten Luksch; Ruth Brenk; Dominic J Campopiano; Michael F Greaney
Journal:  Nat Chem       Date:  2010-05-16       Impact factor: 24.427

2.  trans-Symmetric Dynamic Covalent Systems: Connected Transamination and Transimination Reactions.

Authors:  Fredrik Schaufelberger; Lei Hu; Olof Ramström
Journal:  Chemistry       Date:  2015-06-03       Impact factor: 5.236

Review 3.  Protein-Templated Fragment Ligations-From Molecular Recognition to Drug Discovery.

Authors:  Mike Jaegle; Ee Lin Wong; Carolin Tauber; Eric Nawrotzky; Christoph Arkona; Jörg Rademann
Journal:  Angew Chem Int Ed Engl       Date:  2017-05-31       Impact factor: 15.336

4.  Proteintemplat-gesteuerte Fragmentligationen - von der molekularen Erkennung zur Wirkstofffindung.

Authors:  Mike Jaegle; Ee Lin Wong; Carolin Tauber; Eric Nawrotzky; Christoph Arkona; Jörg Rademann
Journal:  Angew Chem Weinheim Bergstr Ger       Date:  2017-05-31
  4 in total

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