| Literature DB >> 18758489 |
Abstract
Talin can activate integrins to bind the extracellular matrix and also connect matrix-engaged integrins to the actin cytoskeleton. New work shows that cell spreading can be dissected into three distinct phases according to their differential requirements for talin function.Entities:
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Year: 2008 PMID: 18758489 DOI: 10.1038/ncb0908-1017
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824