Literature DB >> 18757061

Understanding the traditional aspect of Chinese medicine in order to achieve meaningful quality control of Chinese materia medica.

Pei-Shan Xie1, Albert Y Leung.   

Abstract

Although sophisticated and technologically advanced, current quality control methods for Chinese medicines (syn. Chinese materia medica or CMM) lack comprehensiveness and practicability. They are more suited for analyzing single-chemical drugs or specific, known chemical components that have already been isolated. While these methods can fully satisfy the modern scientific requirements for identity, purity and quality in the assessment of chemical drugs, they are not suitable for handling the complex chemical nature of traditional CMM whose multifunctional components along with their inherent holistic activities are frequently unknown and thus are not adequately analyzed by these methods. In order to assess properly and meaningfully the identity and quality of complex CMM (also known as Chinese herbs and Chinese herbal medicines), additional measures that can retain the traditional aspect of CMM need to be included. This requires a basic understanding of traditional Chinese medicine (TCM).

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Year:  2008        PMID: 18757061     DOI: 10.1016/j.chroma.2008.08.045

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  25 in total

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4.  Batch-to-batch quality consistency evaluation of botanical drug products using multivariate statistical analysis of the chromatographic fingerprint.

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5.  A strategy for detecting absorbed bioactive compounds for quality control in the water extract of rhubarb by ultra performance liquid chromatography with photodiode array detector.

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7.  The synergism mechanism of Rhubarb Anthraquinones on constipation elucidated by comparative pharmacokinetics of Rhubarb extract between normal and diseased rats.

Authors:  Xiao-Hong Gong; Yan Li; Ruo-Qi Zhang; Xiao-Fang Xie; Cheng Peng; Yun-Xia Li
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2014-07-05       Impact factor: 2.441

8.  Utilization of gene expression signature for quality control of traditional Chinese medicine formula Si-Wu-Tang.

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9.  Traceability and Quality Control in Traditional Chinese Medicine: From Chemical Fingerprint to Two-Dimensional Barcode.

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10.  Harmonization of monographic standards is needed to ensure the quality of Chinese medicinal materials.

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Journal:  Chin Med       Date:  2009-09-22       Impact factor: 5.455

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