Literature DB >> 18754745

Nanotechnology for drug delivery: the perfect partnership.

Omid C Farokhzad.   

Abstract

The pipelines of pharmaceutical companies are in many cases believed to be drying up and many blockbuster drugs are expected to be coming off patent in the near term. The application of nanotechnology to drug delivery is widely expected to create novel therapeutics capable of changing the landscape for pharmaceutical and biotechnology industries. This editorial highlights the nanotechnology platforms that are under development or in clinical use today, and points to exciting areas of opportunity where nanotechnology may enable the development of more effective and safer targeted therapeutics for a myriad of clinical applications.

Mesh:

Year:  2008        PMID: 18754745     DOI: 10.1517/17425247.5.9.927

Source DB:  PubMed          Journal:  Expert Opin Drug Deliv        ISSN: 1742-5247            Impact factor:   6.648


  20 in total

Review 1.  Targeted polymeric therapeutic nanoparticles: design, development and clinical translation.

Authors:  Nazila Kamaly; Zeyu Xiao; Pedro M Valencia; Aleksandar F Radovic-Moreno; Omid C Farokhzad
Journal:  Chem Soc Rev       Date:  2012-03-05       Impact factor: 54.564

2.  Multicomponent amorphous nanofibers electrospun from hot aqueous solutions of a poorly soluble drug.

Authors:  Deng-Guang Yu; Li-Dong Gao; Kenneth White; Christopher Branford-White; Wei-Yue Lu; Li-Min Zhu
Journal:  Pharm Res       Date:  2010-08-19       Impact factor: 4.200

3.  Nitric oxide nanoparticles: pre-clinical utility as a therapeutic for intramuscular abscesses.

Authors:  David Schairer; Luis R Martinez; Karin Blecher; Jason Chouake; Parimala Nacharaju; Philip Gialanella; Joel M Friedman; Joshua D Nosanchuk; Adam Friedman
Journal:  Virulence       Date:  2012-01-01       Impact factor: 5.882

4.  Nanoparticles containing a liver X receptor agonist inhibit inflammation and atherosclerosis.

Authors:  Xue-Qing Zhang; Orli Even-Or; Xiaoyang Xu; Mariska van Rosmalen; Lucas Lim; Suresh Gadde; Omid C Farokhzad; Edward A Fisher
Journal:  Adv Healthc Mater       Date:  2014-08-22       Impact factor: 9.933

5.  Delivery of siRNA to the mouse lung via a functionalized lipopolyamine.

Authors:  Kevin J Polach; Majed Matar; Jennifer Rice; Gregory Slobodkin; Jeff Sparks; Richard Congo; Angela Rea-Ramsey; Diane McClure; Elaine Brunhoeber; Monika Krampert; Andrea Schuster; Kerstin Jahn-Hofmann; Matthias John; Hans-Peter Vornlocher; Jason G Fewell; Khursheed Anwer; Anke Geick
Journal:  Mol Ther       Date:  2011-10-11       Impact factor: 11.454

6.  Nano-polypharmacy to treat tumors: coencapsulation of drug combinations using nanoparticle technology.

Authors:  Frank Alexis
Journal:  Mol Ther       Date:  2014-07       Impact factor: 11.454

7.  Copper-free click-chemistry platform to functionalize cisplatin prodrugs.

Authors:  Rakesh K Pathak; Christopher D McNitt; Vladimir V Popik; Shanta Dhar
Journal:  Chemistry       Date:  2014-04-23       Impact factor: 5.236

Review 8.  Emerging nanotechnology approaches for HIV/AIDS treatment and prevention.

Authors:  Tewodros Mamo; E Ashley Moseman; Nagesh Kolishetti; Carolina Salvador-Morales; Jinjun Shi; Daniel R Kuritzkes; Robert Langer; Ulrich von Andrian; Omid C Farokhzad
Journal:  Nanomedicine (Lond)       Date:  2010-02       Impact factor: 5.307

9.  Modern biotechnology-based therapeutic approaches against HIV infection.

Authors:  Muhammad Imran; Yasir Waheed; Ayesha Ghazal; Sajjad Ullah; Sher Zaman Safi; Muhsin Jamal; Muhammad Ali; Muhammad Atif; Muhammad Imran; Farman Ullah
Journal:  Biomed Rep       Date:  2017-10-24

Review 10.  The Platin-X series: activation, targeting, and delivery.

Authors:  Uttara Basu; Bhabatosh Banik; Ru Wen; Rakesh K Pathak; Shanta Dhar
Journal:  Dalton Trans       Date:  2016-08-16       Impact factor: 4.390

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