Literature DB >> 18754030

Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma.

X Mao, X Li, R Sprangers, X Wang, A Venugopal, T Wood, Y Zhang, D A Kuntz, E Coe, S Trudel, D Rose, R A Batey, L E Kay, A D Schimmer.   

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Year:  2008        PMID： 18754030     DOI： 10.1038/leu.2008.232

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  25 in total

Review 1.  Methyl groups as probes of supra-molecular structure, dynamics and function.

Authors:  Amy M Ruschak; Lewis E Kay
Journal:  J Biomol NMR       Date:  2009-09-27       Impact factor: 2.835

2.  The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity.

Authors:  Biyin Cao; Jie Li; Jingyu Zhu; Mingyun Shen; Kunkun Han; Zubin Zhang; Yang Yu; Yali Wang; Depei Wu; Suning Chen; Aining Sun; Xiaowen Tang; Yun Zhao; Chunhua Qiao; Tingjun Hou; Xinliang Mao
Journal:  J Biol Chem       Date:  2013-10-10       Impact factor: 5.157

3.  The ubiquitin-proteasomal system is critical for multiple myeloma: implications in drug discovery.

Authors:  Biyin Cao; Xinliang Mao
Journal:  Am J Blood Res       Date:  2011-05-25

4.  Novel Quinoline-based Ir(III) Complexes Exhibit High Antitumor Activity in Vitro and in Vivo.

Authors:  Yan Yang; Yi-Dong Bin; Qi-Pin Qin; Xu-Jian Luo; Bi-Qun Zou; Hua-Xin Zhang
Journal:  ACS Med Chem Lett       Date:  2019-11-06       Impact factor: 4.345

Review 5.  The role of allostery in the ubiquitin-proteasome system.

Authors:  Jin Liu; Ruth Nussinov
Journal:  Crit Rev Biochem Mol Biol       Date:  2012-12-13       Impact factor: 8.250

6.  Clioquinol inhibits dopamine-β-hydroxylase secretion and noradrenaline synthesis by affecting the redox status of ATOX1 and copper transport in human neuroblastoma SH-SY5Y cells.

Authors:  Masato Katsuyama; En Kimura; Masakazu Ibi; Kazumi Iwata; Misaki Matsumoto; Nozomi Asaoka; Chihiro Yabe-Nishimura
Journal:  Arch Toxicol       Date:  2020-10-09       Impact factor: 5.153

7.  Supramolecular synthon pattern in solid clioquinol and cloxiquine (APIs of antibacterial, antifungal, antiaging and antituberculosis drugs) studied by ³⁵Cl NQR, ¹H-¹⁷O and ¹H-¹⁴N NQDR and DFT/QTAIM.

Authors:  Jolanta Natalia Latosińska; Magdalena Latosińska; Marzena Agnieszka Tomczak; Janez Seliger; Veselko Zagar
Journal:  J Mol Model       Date:  2010-11-16       Impact factor: 1.810

8.  Pharmacological activity of metal binding agents that alter copper bioavailability.

Authors:  Marian E Helsel; Katherine J Franz
Journal:  Dalton Trans       Date:  2015-05-21       Impact factor: 4.390

9.  Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways.

Authors:  Niall S Kenneth; George E Hucks; Andrew J Kocab; Annie L McCollom; Colin S Duckett
Journal:  Cell Cycle       Date:  2014-02-03       Impact factor: 4.534

10.  The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma.

Authors:  G Wei Xu; Mohsin Ali; Tabitha E Wood; Derek Wong; Neil Maclean; Xiaoming Wang; Marcela Gronda; Marko Skrtic; Xiaoming Li; Rose Hurren; Xinliang Mao; Meenakshi Venkatesan; Reza Beheshti Zavareh; Troy Ketela; John C Reed; David Rose; Jason Moffat; Robert A Batey; Sirano Dhe-Paganon; Aaron D Schimmer
Journal:  Blood       Date:  2010-01-14       Impact factor: 22.113
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