| Literature DB >> 1875339 |
M L Edwards1, R D Snyder, D M Stemerick.
Abstract
The synthesis of a series of novel polyamine analogues is reported. The DNA binding of these compounds and a variety of other polyamines were compared with their IC50 values against HeLa cell. There seemed to be no apparent correlation between the DNA binding and toxicity against HeLa cells.Entities:
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Year: 1991 PMID: 1875339 DOI: 10.1021/jm00112a016
Source DB: PubMed Journal: J Med Chem ISSN: 0022-2623 Impact factor: 7.446