Literature DB >> 18751988

[Self-limitation of inflammatory T-cell responses. Help to self-help as a therapeutic concept].

S Rutz1, A Scheffold.   

Abstract

Regulatory T cells are in the focus of research on autoimmunity. However, recent findings suggest that pro-inflammatory T(H)1 cells themselves exert important immunoregulatory functions. This physiological self-limiting mechanism holds great promise for therapeutic interventions.

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Year:  2008        PMID： 18751988     DOI： 10.1007/s00393-008-0343-0

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN： 0340-1855            Impact factor:   1.372


  4 in total

Review 1.  Notch signalling during peripheral T-cell activation and differentiation.

Authors:  Barbara A Osborne; Lisa M Minter
Journal:  Nat Rev Immunol       Date:  2006-12-15       Impact factor: 53.106

Review 2.  Regulatory T cells: development, function and role in autoimmunity.

Authors:  Ruth Y Lan; Aftab A Ansari; Zhe-Xiong Lian; M Eric Gershwin
Journal:  Autoimmun Rev       Date:  2005-03-07       Impact factor: 9.754

3.  Notch regulates IL-10 production by T helper 1 cells.

Authors:  Sascha Rutz; Marko Janke; Nadine Kassner; Thordis Hohnstein; Manuela Krueger; Alexander Scheffold
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-21       Impact factor: 11.205

Review 4.  Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10.

Authors:  Ming O Li; Richard A Flavell
Journal:  Immunity       Date:  2008-04       Impact factor: 31.745
  4 in total

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