OBJECTIVE: To examine whether in utero exposure to uterotonic drugs effects cognitive performance in draft-age men. DESIGN: Historical cohort study based on birth registry data and cognitive function measured during evaluations for military service. SUBJECTS: 4300 Danish conscripts born between 1973 and 1975. MAIN OUTCOME MEASURES: MEAN SCORE IN THE BOERGE PRIEN TEST OF COGNITIVE FUNCTION: score is the number of correct answers to 78 questions and correlates with the full scale intelligence quotient. RESULTS: The mean Boerge Prien score was similar for those exposed (n=1011) to uterotonic drugs and those not exposed (n=3289), 43.1 versus 42.9 after adjustment for confounders. CONCLUSION: Our data indicate that exposure to uterotonic drugs does not affect cognitive function 20 years later.
OBJECTIVE: To examine whether in utero exposure to uterotonic drugs effects cognitive performance in draft-age men. DESIGN: Historical cohort study based on birth registry data and cognitive function measured during evaluations for military service. SUBJECTS: 4300 Danish conscripts born between 1973 and 1975. MAIN OUTCOME MEASURES: MEAN SCORE IN THE BOERGE PRIEN TEST OF COGNITIVE FUNCTION: score is the number of correct answers to 78 questions and correlates with the full scale intelligence quotient. RESULTS: The mean Boerge Prien score was similar for those exposed (n=1011) to uterotonic drugs and those not exposed (n=3289), 43.1 versus 42.9 after adjustment for confounders. CONCLUSION: Our data indicate that exposure to uterotonic drugs does not affect cognitive function 20 years later.