Literature DB >> 1874601

Mitoxantrone, etoposide, mitoguazone and vinblastine chemotherapy (MV2) in relapsed and refractory lymphomas.

J P Crown1, S Gulati, D J Straus, J Kolitz, R Heelan, J O'Brien, B J Lee, C Portlock, J Bertino.   

Abstract

As part of a program to develop less leukemogenic chemotherapy regimens for the treatment of favorable prognosis Hodgkin's disease, a phase I-II trial of mitoxantrone, etoposide, mitoguazone, and vinblastine was used to treat patients with relapsed and refractory malignant lymphoma and Hodgkin's disease. An overall partial response rate of 41% was observed. Although useful responses were seen, the absence of complete remissions is disappointing.

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Year:  1991        PMID: 1874601     DOI: 10.1007/bf00175086

Source DB:  PubMed          Journal:  Invest New Drugs        ISSN: 0167-6997            Impact factor:   3.850


  3 in total

1.  Risk of second cancers after treatment for Hodgkin's disease.

Authors:  M A Tucker; C N Coleman; R S Cox; A Varghese; S A Rosenberg
Journal:  N Engl J Med       Date:  1988-01-14       Impact factor: 91.245

Review 2.  Salvage therapy of advanced Hodgkin's disease. Critical appraisal of curative potential.

Authors:  A C Buzaid; S M Lippman; T P Miller
Journal:  Am J Med       Date:  1987-09       Impact factor: 4.965

Review 3.  Concomitant illness in patients treated for Hodgkin's disease.

Authors:  M A Bookman; D L Longo
Journal:  Cancer Treat Rev       Date:  1986-06       Impact factor: 12.111

  3 in total

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