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Literature DB >> 1873854

Antigens of melanocytes and melanoma.

S A Lynch¹, B N Bouchard, S Vijayasaradhi, H Yuasa, A N Houghton.

Abstract

Melanoma is a valuable model to study phenotypic traits that are regulated during cell differentiation and malignant transformation. Melanoma cells display extensive phenotypic and antigenic heterogeneity. Studies of this attribute have provided insight into events that take place during normal melanocyte differentiation and give clues to traits that contribute to malignancy. It is possible that the phenotypic and genotypic heterogeneity present among melanoma cells within a single lesion includes a subset of cells with traits that favor tumor progression and metastasis. This review discusses the identification and characterization of antigens expressed by melanoma cells and their potential contribution to melanocyte differentiation and malignant transformation.

Entities: Disease

Mesh：

Substances：

Year: 1991 PMID： 1873854 DOI： 10.1007/bf00049411

Source DB: PubMed Journal: Cancer Metastasis Rev ISSN： 0167-7659 Impact factor: 9.264

35 in total

1. Extracellular matrix-modulated expression of human cell surface glycoproteins A42 and J143. Intrinsic and extrinsic signals determine antigenic phenotype.

Authors: W J Rettig; V V Murty; M J Mattes; R S Chaganti; L J Old
Journal: J Exp Med Date: 1986-11-01 Impact factor: 14.307

Review 2. The migration and differentiation of neural crest cells.

Authors: J A Weston
Journal: Adv Morphog Date: 1970

3. Common human melanoma-associated antigen(s) detected by monoclonal antibodies.

Authors: S Carrel; R S Accolla; A L Carmagnola; J P Mach
Journal: Cancer Res Date: 1980-07 Impact factor: 12.701

4. Purification of an autoantigenic 75-kDa human melanosomal glycoprotein.

Authors: S Vijayasaradhi; A N Houghton
Journal: Int J Cancer Date: 1991-01-21 Impact factor: 7.396

5. Sialyltransferase levels and ganglioside expression in melanoma and other cultured human cancer cells.

Authors: I J Thampoe; K Furukawa; E Vellvé; K O Lloyd
Journal: Cancer Res Date: 1989-11-15 Impact factor: 12.701

6. Monoclonal antibody to an intracellular antigen images human melanoma transplants in nu/nu mice.

Authors: S Welt; M J Mattes; R Grando; T M Thomson; R W Leonard; P B Zanzonico; R E Bigler; S Yeh; H F Oettgen; L J Old
Journal: Proc Natl Acad Sci U S A Date: 1987-06 Impact factor: 11.205

7. Serological survey of normal humans for natural antibody to cell surface antigens of melanoma.

Authors: A N Houghton; M C Taormina; H Ikeda; T Watanabe; H F Oettgen; L J Old
Journal: Proc Natl Acad Sci U S A Date: 1980-07 Impact factor: 11.205

8. The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product.

Authors: S Vijayasaradhi; B Bouchard; A N Houghton
Journal: J Exp Med Date: 1990-04-01 Impact factor: 14.307

9. Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets.

Authors: A N Houghton; M Eisinger; A P Albino; J G Cairncross; L J Old
Journal: J Exp Med Date: 1982-12-01 Impact factor: 14.307

10. Induction of pigmentation in mouse fibroblasts by expression of human tyrosinase cDNA.

Authors: B Bouchard; B B Fuller; S Vijayasaradhi; A N Houghton
Journal: J Exp Med Date: 1989-06-01 Impact factor: 14.307

5 in total

1. CD44/chondroitin sulfate proteoglycan and alpha 2 beta 1 integrin mediate human melanoma cell migration on type IV collagen and invasion of basement membranes.

Authors: J R Knutson; J Iida; G B Fields; J B McCarthy
Journal: Mol Biol Cell Date: 1996-03 Impact factor: 4.138