Literature DB >> 1873426

[An electrolyte-adapted heparin solution for the determination of blood gases and electrolytes in whole blood].

O Müller-Plathe1, R Schreiber.   

Abstract

Blood gases, pH, sodium, potassium, chloride, and ionised calcium in whole blood samples can be determined simultaneously in modern instruments. Preparing syringes with conventional heparin solutions causes a relevant bias of the electrolyte concentrations (especially K+ and Ca2+) by dilution of the sample. Additionally, ionised calcium is decreased by binding to heparin. The solution described in the present paper yields a final heparin concentration of 4-6 mU/l, thus eliminating the calcium binding effect. The dilution effects are antagonised by an electrolyte composition that is similar to normal plasma. The heparin solution is commercially available.

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Year:  1991        PMID: 1873426     DOI: 10.1055/s-2007-1000556

Source DB:  PubMed          Journal:  Anasthesiol Intensivmed Notfallmed Schmerzther        ISSN: 0939-2661            Impact factor:   0.698


  1 in total

1.  Evaluation of the AVOXimeter: precision, long-term stability, linearity, and use without heparin.

Authors:  S R Bailey; E L Russell; A Martinez
Journal:  J Clin Monit       Date:  1997-05
  1 in total

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