| Literature DB >> 1873302 |
J M García Fraga1, A I Jiménez Abizanda, F Jiménez Moreno, J J Arias León.
Abstract
Three methods are proposed for the simultaneous determination of imipramine and amitryptiline by derivative spectrophotometry, one of them using both first- and second-derivative spectra, and the others using the first- and second-derivative spectra, respectively, obtained from a "diode array" spectrophotometer. The methods allow the determination of 0.62-10.14 micrograms ml-1 of imipramine, and 0.63-10.04 micrograms ml-1 of amitryptiline, and have been applied to their determination in blood serum.Entities:
Mesh：
Substances：
Year: 1991 PMID： 1873302 DOI： 10.1016/0731-7085(91)80133-t
Source DB: PubMed Journal: J Pharm Biomed Anal ISSN： 0731-7085 Impact factor: 3.935