Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Carnosine [corrected] increases efficiency of DOPA therapy of Parkinson's disease: a pilot study.

Literature DB >> 18729814

Carnosine [corrected] increases efficiency of DOPA therapy of Parkinson's disease: a pilot study.

Alexander Boldyrev¹, Tatiana Fedorova, Maria Stepanova, Irina Dobrotvorskaya, Eugenia Kozlova, Natalia Boldanova, Gulbakhar Bagyeva, Irina Ivanova-Smolenskaya, Serguey Illarioshkin.

Abstract

The addition of the neuropeptide carnosine (beta-alanyl-L-histidine) as a food additive to the basic protocol of Parkinson's disease treatment results in significant improvement of neurological symptoms, along with increase in red blood cell Cu/Zn-SOD and decrease in blood plasma protein carbonyls and lipid hydroperoxides, with no noticeable change in platelets MAO B activity. The combination of carnosine with basic therapy may be a useful way to increase efficiency of PD treatment.

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 2008 PMID： 18729814 DOI： 10.1089/rej.2008.0716

Source DB: PubMed Journal: Rejuvenation Res ISSN： 1549-1684 Impact factor: 4.663

Keyword Cloud
Cited

34 in total

1. Neuroprotective effect of carnosine in the olfactory bulb after vanadium inhalation in a mouse model.

Authors: Laura Colín-Barenque; Patricia Bizarro-Nevares; Adriana González Villalva; Jose Pedraza-Chaverri; Omar Noel Medina-Campos; Ruben Jimenez-Martínez; Daniela S Rodríguez-Rangel; Stefanie Reséndiz; Teresa I Fortoul
Journal: Int J Exp Pathol Date: 2018-09-09 Impact factor: 1.925

2. Acute Carnosine Administration Increases Respiratory Chain Complexes and Citric Acid Cycle Enzyme Activities in Cerebral Cortex of Young Rats.

Authors: Levy W Macedo; José H Cararo; Soliany G Maravai; Cinara L Gonçalves; Giovanna M T Oliveira; Luiza W Kist; Camila Guerra Martinez; Eleonora Kurtenbach; Maurício R Bogo; Alan R Hipkiss; Emilio L Streck; Patrícia F Schuck; Gustavo C Ferreira
Journal: Mol Neurobiol Date: 2015-10-17 Impact factor: 5.590

Review 9. Glycotoxins: Dietary and Metabolic Origins; Possible Amelioration of Neurotoxicity by Carnosine, with Special Reference to Parkinson's Disease.

Authors: Alan R Hipkiss
Journal: Neurotox Res Date: 2018-02-07 Impact factor: 3.911

10. Use of carnosine in the prevention of cardiometabolic risk factors in overweight and obese individuals: study protocol for a randomised, double-blind placebo-controlled trial.

Authors: Kirthi Menon; James D Cameron; Maximilian de Courten; Barbora de Courten
Journal: BMJ Open Date: 2021-05-13 Impact factor: 2.692

Carnosine [corrected] increases efficiency of DOPA therapy of Parkinson's disease: a pilot study.

1. Neuroprotective effect of carnosine in the olfactory bulb after vanadium inhalation in a mouse model.

2. Acute Carnosine Administration Increases Respiratory Chain Complexes and Citric Acid Cycle Enzyme Activities in Cerebral Cortex of Young Rats.

Review 3. Carnosine and Related Peptides: Therapeutic Potential in Age-Related Disorders.

4. A Systematic Risk Assessment and Meta-Analysis on the Use of Oral β-Alanine Supplementation.

5. Carnosine exerts neuroprotective effect against 6-hydroxydopamine toxicity in hemiparkinsonian rat.

6. Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates.

7. Reactive Carbonyl Species Scavengers-Novel Therapeutic Approaches for Chronic Diseases.

8. Biological activity of novel synthetic derivatives of carnosine.

Review 9. Glycotoxins: Dietary and Metabolic Origins; Possible Amelioration of Neurotoxicity by Carnosine, with Special Reference to Parkinson's Disease.

10. Use of carnosine in the prevention of cardiometabolic risk factors in overweight and obese individuals: study protocol for a randomised, double-blind placebo-controlled trial.