Literature DB >> 18729151

Carotid angioplasty and stenting in octogenarians: is it safe?

M Henry1,2, I Henry3, A Polydorou4, M Hugel1,2.   

Abstract

PURPOSE: Elderly patients have a higher risk of complications in carotid endarterectomy. The aim of the study was to evaluate whether carotid artery stenting (CAS) performed in octogenarians also increases the procedure related risk.
METHODS: 870 patients (male 626) mean age 70.9 +/- 9.3 years underwent 930 CAS for de novo lesions (n = 851) restenoses (n = 54) post radiation (n = 14) inflammatory arteritis (n = 9) post trauma aneurysms (n = 2). Indications for treatment: symptomatic carotid stenosis > or = 70% (n = 577) or asymptomatic stenosis > or = 80%. Patients were separated into two age groups: <80 years (749 patients, 806 CAS) and >80 years (121 patients, 124 CAS). 187 CAS performed without protection (N.P-) 6 patients >80 years, 743 with protection (NP+) (occlusion balloon: 334, filters: 404, reversal flow: 6) 118 patients >80 years. Data analysis included neurological complications, death and myocardial infarction (MI) rate at 30 days, anatomical particularities. Technical points will be described depending on the age of the patient.
RESULTS: Technical success 804/806 in patients <80 years, 123/124 in patients >80 years (NS). 30 days outcomes: in the patient group <80 years we observed 9 TIA (1.1%) 3 without NP (1.7%) 6 with NP (0.9%), 5 minor strokes (0.6%) 2 without NP (1.1%) 3 with NP (0.5%), 3 major strokes: 2 without NP (1.1%) 1 with NP (0.2%), 5 deaths (0.6%) 2 without NP (1.1%) 3 with NP (0.5%). Death/stroke/MI: 14 (1.8%) 6 without NP (3.3%), 8 with NP (1.3%). In the group >80 years, we observed 2 TIA (1.7%) 1 without NP 1 with NP (0.92%) 1 minor stroke without NP (17%) no major stroke, no death. Death/stroke/MI 1 without NP (17%).
CONCLUSION: CAS can be performed in elderly patients without higher risk than in younger patients. But good indications, a meticulous technique, protection devices are mandatory and some technical points must be pointed out to avoid neurological complications and failures. Copyright 2008 Wiley-Liss, Inc.

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Year:  2008        PMID: 18729151     DOI: 10.1002/ccd.21574

Source DB:  PubMed          Journal:  Catheter Cardiovasc Interv        ISSN: 1522-1946            Impact factor:   2.692


  8 in total

1.  Carotid artery stenting in asymptomatic and surgically high-risk patients: single-centre, single-operator results.

Authors:  Josef Veselka; Petra Zimolová; Daniela Cerná; Pavel Stanka; Aleš Tomek; Martin Srámek
Journal:  Int J Angiol       Date:  2008

2.  The Carotid Revascularization Endarterectomy versus Stenting Trial: credentialing of interventionalists and final results of lead-in phase.

Authors:  L Nelson Hopkins; Gary S Roubin; Elie Y Chakhtoura; William A Gray; Robert D Ferguson; Barry T Katzen; Kenneth Rosenfield; Jonathan Goldstein; Donald E Cutlip; William Morrish; Brajesh K Lal; Alice J Sheffet; MeeLee Tom; Susan Hughes; Jenifer Voeks; Krishna Kathir; James F Meschia; Robert W Hobson; Thomas G Brott
Journal:  J Stroke Cerebrovasc Dis       Date:  2010-03       Impact factor: 2.136

3.  Stroke prevention: carotid stenting versus carotid endarterectomy.

Authors:  Christopher J White
Journal:  F1000 Med Rep       Date:  2010-03-25

4.  Carotid revascularization using endarterectomy or stenting systems (CaRESS): 4-year outcomes.

Authors:  Christopher K Zarins; Rodney A White; Edward B Diethrich; Rebecca J Shackelton; Flora S Siami
Journal:  J Endovasc Ther       Date:  2009-08       Impact factor: 3.487

5.  Carotid stenting in a nonagenarian patient with symptomatic carotid stenosis.

Authors:  Ranjan Shetty K; Vivek G; Manoj K Gupta; Krishananda Nayak; Umesh Pai; Lorraine Dias; Kushal Naha; Raviraj Acharya
Journal:  Australas Med J       Date:  2012-10-31

6.  Is age of 80 years a threshold for carotid revascularization?

Authors:  Boudewijn L Reichmann; Guus W van Lammeren; Frans L Moll; Gert J de Borst
Journal:  Curr Cardiol Rev       Date:  2011-02

Review 7.  Clinical Outcomes of Second- versus First-Generation Carotid Stents: A Systematic Review and Meta-Analysis.

Authors:  Adam Mazurek; Krzysztof Malinowski; Kenneth Rosenfield; Laura Capoccia; Francesco Speziale; Gianmarco de Donato; Carlo Setacci; Christian Wissgott; Pasqualino Sirignano; Lukasz Tekieli; Andrey Karpenko; Waclaw Kuczmik; Eugenio Stabile; David Christopher Metzger; Max Amor; Adnan H Siddiqui; Antonio Micari; Piotr Pieniążek; Alberto Cremonesi; Joachim Schofer; Andrej Schmidt; Piotr Musialek
Journal:  J Clin Med       Date:  2022-08-17       Impact factor: 4.964

Review 8.  Selective-versus-Standard Poststent Dilation for Carotid Artery Disease: A Systematic Review and Meta-Analysis.

Authors:  O Petr; W Brinjikji; M H Murad; B Glodny; G Lanzino
Journal:  AJNR Am J Neuroradiol       Date:  2017-03-16       Impact factor: 3.825

  8 in total

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