Heterogeneous gold catalysts for efficient access to functionalized lactones.

A novel class of heterogeneous gold catalysts supported on zeolite beta-NH4+ was prepared by the deposition-precipitation method. This new class of catalyst showed interesting catalytic activities for the intramolecular cycloisomerization of gamma-acetylenic carboxylic acids leading to functionalized gamma-alkylidene gamma-butyrolactones. Analysis of the supported gold species with in situ X-ray photoelectron spectroscopy (in situ XPS) suggests that cationic Au (possibly AuIII) can play an important role in such reactions. The high discrepancy in catalyst stability in favor of the Au supported on the zeolite system over bulk Au2O3 is explained by 1) the size of the particles and 2) the reversibility of the redox deactivating process (AuIII-->AuI) in the presence of oxygen for the supported system. The efficiency of this system allowed reaction under mild heterogeneous conditions. The potential for catalyst recycling was also highlighted.