Literature DB >> 18727692

Alexis Carrel: genius, innovator and ideologist.

P Dutkowski1, O de Rougemont, P-A Clavien.   

Abstract

Alexis Carrel was a Frenchman from Lyon, who gained fame at the Rockefeller Institute in New York at the beginning of the 20th century. He was the first to demonstrate that arteriovenous anastomoses were possible. Alexis Carrel was awarded the Nobel Prize for his contributions to vascular surgery and transplantation in 1912. He was a versatile scientist, who made numerous discoveries from the design of an antiseptic solution to treat injuries during the First World War to tissue culture and engineering, and organ preservation, making him the father of solid organ transplantation. Together, with the famous aviator and engineer Charles Lindbergh, they were the first scientists capable of keeping an entire organ alive outside of the body, using a perfusion machine. Due to his many dubious ideas and his association with fascism in the 1930s and during the Second World War, many of his scientific achievements have been forgotten today and taken for granted.

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Year:  2008        PMID: 18727692     DOI: 10.1111/j.1600-6143.2008.02364.x

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  8 in total

1.  Alexis Carrel: 'father of transplant surgery' and supporter of eugenics.

Authors:  Gervase Vernon
Journal:  Br J Gen Pract       Date:  2019-07       Impact factor: 5.386

Review 2.  Machine perfusion strategies in liver transplantation.

Authors:  Andrea Schlegel; Xavier Muller; Philipp Dutkowski
Journal:  Hepatobiliary Surg Nutr       Date:  2019-10       Impact factor: 7.293

Review 3.  Bioengineering kidneys for transplantation.

Authors:  Maria Lucia L Madariaga; Harald C Ott
Journal:  Semin Nephrol       Date:  2014-06-13       Impact factor: 5.299

Review 4.  Hypothermic Oxygenated Liver Perfusion: Basic Mechanisms and Clinical Application.

Authors:  A Schlegel; P Kron; P Dutkowski
Journal:  Curr Transplant Rep       Date:  2015

Review 5.  Hypothermic Machine Preservation of the Liver: State of the Art.

Authors:  Andrea Schlegel; Xavier Muller; Philipp Dutkowski
Journal:  Curr Transplant Rep       Date:  2018-01-22

6.  In Situ Polyphosphate Nanoparticle Formation in Hybrid Poly(vinyl alcohol)/Karaya Gum Hydrogels: A Porous Scaffold Inducing Infiltration of Mesenchymal Stem Cells.

Authors:  Emad Tolba; Xiaohong Wang; Maximilian Ackermann; Meik Neufurth; Rafael Muñoz-Espí; Heinz C Schröder; Werner E G Müller
Journal:  Adv Sci (Weinh)       Date:  2018-11-13       Impact factor: 16.806

Review 7.  Regenerative Medicine in Organ and Tissue Transplantation: Shortly and Practically Achievable?

Authors:  A Heidary Rouchi; M Mahdavi-Mazdeh
Journal:  Int J Organ Transplant Med       Date:  2015-08-01

Review 8.  Polyethylene Glycol 35 as a Perfusate Additive for Mitochondrial and Glycocalyx Protection in HOPE Liver Preservation.

Authors:  Arnau Panisello Rosello; Rui Teixeira da Silva; Carlos Castro; Raquel G Bardallo; Maria Calvo; Emma Folch-Puy; Teresa Carbonell; Carlos Palmeira; Joan Roselló Catafau; René Adam
Journal:  Int J Mol Sci       Date:  2020-08-09       Impact factor: 5.923

  8 in total

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