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Literature DB >> 18726560

Antibacterial activity of two limonoids from Swietenia mahagoni against multiple-drug-resistant (MDR) bacterial strains.

A K M Shahidur Rahman¹, A K Azad Chowdhury, Husne-Ara Ali, Sheikh Z Raihan, Mohammad S Ali, Lutfun Nahar, Satyajit D Sarker.

Abstract

Solvent partitioning followed by column chromatography of the MeOH extract of the seeds of Swietenia mahagoni afforded two limonoids, swietenolide (1) and 2-hydroxy-3-O-tigloylswietenolide (2). The compounds were identified by spectroscopic means. The antibacterial activity of these compounds was assessed against eight multiple-drug-resistant bacterial strains (clinical isolates) by the conventional disc diffusion method. While both compounds were active against all test organisms, compound 2 displayed overall more potent activity than compound 1.

Entities: Chemical Species

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Year: 2008 PMID： 18726560 DOI： 10.1007/s11418-008-0287-3

Source DB: PubMed Journal: J Nat Med ISSN： 1340-3443 Impact factor: 2.343

8 in total

1. Antibacterial and antifungal activity of Indonesian ethnomedical plants.

Authors: E Goun; G Cunningham; D Chu; C Nguyen; D Miles
Journal: Fitoterapia Date: 2003-09 Impact factor: 2.882

2. Antibiotic susceptibility testing by a standardized single disk method.

Authors: A W Bauer; W M Kirby; J C Sherris; M Turck
Journal: Am J Clin Pathol Date: 1966-04 Impact factor: 2.493

3. Platelet aggregation inhibitors from the seeds of Swietenia mahagoni: inhibition of in vitro and in vivo platelet-activating factor-induced effects of tetranortriterpenoids related to swietenine and swietenolide.

Authors: H Ekimoto; Y Irie; Y Araki; G Q Han; S Kadota; T Kikuchi
Journal: Planta Med Date: 1991-02 Impact factor: 3.352

4. Swietenia mahagony extract shows agonistic activity to PPAR(gamma) and gives ameliorative effects on diabetic db/db mice.

Authors: Dan-Dan Li; Jun-Hua Chen; Qing Chen; Guo-Wei Li; Jing Chen; Jian-Min Yue; Min-Li Chen; Xiao-Ping Wang; Jian-Hua Shen; Xu Shen; Hua-Liang Jiang
Journal: Acta Pharmacol Sin Date: 2005-02 Impact factor: 6.150

5. Rings B,D-seco limonoids from the leaves of Swietenia mahogani.

Authors: Samir A M Abdelgaleil; Matsumi Doe; Yoshiki Morimoto; Munehiro Nakatani
Journal: Phytochemistry Date: 2006-01-26 Impact factor: 4.072

6. Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo-2 colon cancer cell line in vitro.

Authors: Shaikh J Uddin; Lutfun Nahar; Jamil A Shilpi; Mohammad Shoeb; Tomasz Borkowski; Simon Gibbons; Moira Middleton; Maureen Byres; Satyajit D Sarker
Journal: Phytother Res Date: 2007-08 Impact factor: 5.878

7. Pachypodol, a flavonol from the leaves of Calycopteris floribunda, inhibits the growth of CaCo 2 colon cancer cell line in vitro.

Authors: Husne-Ara Ali; A K Azad Chowdhury; Abul K M Rahman; Tomasz Borkowski; Lutfun Nahar; Satyajit D Sarker
Journal: Phytother Res Date: 2008-12 Impact factor: 5.878

8. Swarnalin and cis-swarnalin, two new tetrahydrofuran derivatives with free radical scavenging activity, from the aerial parts of Cuscuta reflexa.

Authors: Shaikh J Uddin; Jamil A Shilpi; Moira Middleton; Maureen Byres; Mohammad Shoeb; Lutfun Nahar; Satyajit D Sarker
Journal: Nat Prod Res Date: 2007-06 Impact factor: 2.861

8 in total

8. The Untargeted Phytochemical Profile of Three Meliaceae Species Related to In Vitro Cytotoxicity and Anti-Virulence Activity against MRSA Isolates.

Authors: Leilei Zhang; Maha M Ismail; Gabriele Rocchetti; Nesrin M Fayek; Luigi Lucini; Fatema R Saber
Journal: Molecules Date: 2022-01-10 Impact factor: 4.411

8 in total

Antibacterial activity of two limonoids from Swietenia mahagoni against multiple-drug-resistant (MDR) bacterial strains.

1. Antibacterial and antifungal activity of Indonesian ethnomedical plants.

2. Antibiotic susceptibility testing by a standardized single disk method.

3. Platelet aggregation inhibitors from the seeds of Swietenia mahagoni: inhibition of in vitro and in vivo platelet-activating factor-induced effects of tetranortriterpenoids related to swietenine and swietenolide.

4. Swietenia mahagony extract shows agonistic activity to PPAR(gamma) and gives ameliorative effects on diabetic db/db mice.

5. Rings B,D-seco limonoids from the leaves of Swietenia mahogani.

6. Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo-2 colon cancer cell line in vitro.

7. Pachypodol, a flavonol from the leaves of Calycopteris floribunda, inhibits the growth of CaCo 2 colon cancer cell line in vitro.

8. Swarnalin and cis-swarnalin, two new tetrahydrofuran derivatives with free radical scavenging activity, from the aerial parts of Cuscuta reflexa.

Review 1. Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens.

Review 2. The Prospects of Swietenia macrophylla King in Skin Care.

3. Bioactivity studies on Musa seminifera Lour.

4. Limonoids from Melia azedarach Fruits as Inhibitors of Flaviviruses and Mycobacterium tubercolosis.

5. Diterpenoids and Limonoids from the Leaves and Twigs of Swietenia mahagoni.

Review 6. Chemical Structures and Biological Activities of Limonoids from the Genus Swietenia (Meliaceae).

Review 7. The recent use of Swietenia mahagoni (L.) Jacq. as antidiabetes type 2 phytomedicine: A systematic review.

8. The Untargeted Phytochemical Profile of Three Meliaceae Species Related to In Vitro Cytotoxicity and Anti-Virulence Activity against MRSA Isolates.