| Literature DB >> 18726554 |
A Ramos1, L Ley, E Muñez, A Videl, I Sánchez.
Abstract
Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that exhibits highly specific lytic activity against polymorphonuclear cells, monocytes, and macrophages. A 34-year-old man admitted for right parietal brain abscess and thickened dura mater in close proximity to a lytic bone lesion is presented. The abscess culture yielded methicillin-sensitive S. aureus that produced PVL. The patient did well after surgery and antibiotic treatment. A hematogenous infection, route of bone infection with progression to dura mater and brain parenchyma was hypothesized. To our knowledge this is the first reported case of a brain abscess due to PVL-positive S. aureus.Entities:
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Year: 2008 PMID: 18726554 DOI: 10.1007/s15010-008-7364-0
Source DB: PubMed Journal: Infection ISSN: 0300-8126 Impact factor: 3.553