Literature DB >> 18725695

Mechanical characterization of ultra-high molecular weight polyethylene-hydroxyapatite nanocomposites.

J Crowley1, V B Chalivendra.   

Abstract

An experimental study of Ultra-High Molecular Weight Polyethylene (UHMWPE) and hydroxyapatite (HAP) nanocomposites for the purpose of joint prosthesis is investigated under quasi-static and dynamic loading conditions. By employing compression mold process, five different volume fractions of hydroxyapatite nanoparticle reinforced nanocomposites are made. Quasi-static tension and compression tests are performed using ASTM test methods. Dynamic compression characterization is performed using split Hopkinson pressure bar technique. The nanocomposite performance as a function of volume fraction under a typical loading rate is investigated. The results of the fabricated nanocomposites are compared with currently employed UHMWPE in the joint implants. For comparison purposes, separate sets of tests are performed on currently employed UHMWPE. This comparison provides a valid measure to identify the optimum volume fraction of hydroxyapatite that can be used without compromising the integrity of the UHMPWPE in joint prosthesis.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18725695

Source DB:  PubMed          Journal:  Biomed Mater Eng        ISSN: 0959-2989            Impact factor:   1.300


  3 in total

1.  Biphasic peptide amphiphile nanomatrix embedded with hydroxyapatite nanoparticles for stimulated osteoinductive response.

Authors:  Joel M Anderson; Jessica L Patterson; Jeremy B Vines; Amjad Javed; Shawn R Gilbert; Ho-Wook Jun
Journal:  ACS Nano       Date:  2011-11-17       Impact factor: 15.881

2.  Early osteogenic signal expression of rat bone marrow stromal cells is influenced by both hydroxyapatite nanoparticle content and initial cell seeding density in biodegradable nanocomposite scaffolds.

Authors:  Kyobum Kim; David Dean; Anqi Lu; Antonios G Mikos; John P Fisher
Journal:  Acta Biomater       Date:  2010-11-11       Impact factor: 8.947

3.  Hydroxyapatite nanoparticle reinforced peptide amphiphile nanomatrix enhances the osteogenic differentiation of mesenchymal stem cells by compositional ratios.

Authors:  Jeremy B Vines; Dong-Jin Lim; Joel M Anderson; Ho-Wook Jun
Journal:  Acta Biomater       Date:  2012-07-25       Impact factor: 8.947

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.